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- W2041497963 abstract "Th e salbutamol mucoadhesive tablets were prepared with objective of avoiding first pass metabolism and prolonging duration of action. Salbutamol mucoadhesive bi layered tablets were prepared by a direct compression method using bio adh esive polymers such as Carbopol - 934, PVP and PVA along with ethyl cellulose as backing layer. The interaction between the excipcents and salbutamol was also studied through FTIR spectroscopy. Tablets were evaluated for their physical proper ties like hardness, friability and weig ht variation, uniformity of thickness, content uniformity and in vitro swelling study. I n - vitro release studies of formulations were performed and data obtained from in - vitro release study were fitted to various kinetic models. The prepared formulations we re passed the evaluation tests and the mechanism of drug release from tablets was found to be Quasi - Fickian Diffusion transport." @default.
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- W2041497963 date "2014-05-29" @default.
- W2041497963 modified "2023-10-14" @default.
- W2041497963 title "DESIGN AND EVALUATION OF MUCOADHESIVE BILAYER TABLETS OF SALBUTAMOL SULPHATE" @default.
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- W2041497963 doi "https://doi.org/10.7897/2230-8407.050576" @default.
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