FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2041535436> ?p ?o ?g. }

• W2041535436 endingPage "615" @default.
• W2041535436 startingPage "610" @default.
• W2041535436 abstract "G proteins play vital roles in cellular responses to external signals. The specificity of G protein-receptor interaction is mediated mostly by the gamma-subunit and the individual members of the gamma-subunit multigene family would hence be expected to each have a particular expression profile. In an experiment designed to isolate genes expressed predominantly in human testis we identified a cDNA fragment corresponding to the gamma2 gene. Although the protein sequence of the gamma2 subunit has previously been published, the cDNA sequence, expression pattern, genomic structure, and localisation of the human GNG2 gene have not been described. We report the complete sequence of the GNG2 cDNA which is 1066 bp long and contains an open reading frame encoding a protein of 71 amino acids. This protein is 100% homologous to the bovine, mouse, and rat G protein gamma2 subunit. The gene structure is very similar to that of other Ggamma-subunit genes in that there are two introns, one located in the 5' UTR and the other within the ORF. We show that this gene is expressed in a range of foetal tissues as well as adult testis, adrenal gland, brain, white blood cells and lung but not in adult liver, muscle, sperm, prostate gland nor in the testes of two different infertile patients. There is evidence that GNG2 is expressed in malignant tissues. Using two independent methods, we have mapped the human GNG2 gene to chromosome 14q21." @default.
• W2041535436 created "2016-06-24" @default.
• W2041535436 creator A5033787859 @default.
• W2041535436 creator A5048774381 @default.
• W2041535436 creator A5049295113 @default.
• W2041535436 date "2000-06-01" @default.
• W2041535436 modified "2023-09-25" @default.
• W2041535436 title "Cloning, Characterization, and Mapping of the Gene Encoding the Human G Protein γ 2 Subunit" @default.
• W2041535436 cites W1507458700 @default.
• W2041535436 cites W1527306897 @default.
• W2041535436 cites W1550872707 @default.
• W2041535436 cites W1681309649 @default.
• W2041535436 cites W1963595092 @default.
• W2041535436 cites W1965404955 @default.
• W2041535436 cites W1978368163 @default.
• W2041535436 cites W1983474578 @default.
• W2041535436 cites W1985459812 @default.
• W2041535436 cites W1992965538 @default.
• W2041535436 cites W1995522877 @default.
• W2041535436 cites W2000103116 @default.
• W2041535436 cites W2003248941 @default.
• W2041535436 cites W2007971181 @default.
• W2041535436 cites W2008281092 @default.
• W2041535436 cites W2022807139 @default.
• W2041535436 cites W2025343301 @default.
• W2041535436 cites W2025409698 @default.
• W2041535436 cites W2025437968 @default.
• W2041535436 cites W2028400715 @default.
• W2041535436 cites W2030345162 @default.
• W2041535436 cites W2036272341 @default.
• W2041535436 cites W2040452285 @default.
• W2041535436 cites W2052845309 @default.
• W2041535436 cites W2059659204 @default.
• W2041535436 cites W2063573121 @default.
• W2041535436 cites W2068502127 @default.
• W2041535436 cites W2080875376 @default.
• W2041535436 cites W2088452472 @default.
• W2041535436 cites W2094263431 @default.
• W2041535436 cites W2109283410 @default.
• W2041535436 cites W2139069650 @default.
• W2041535436 cites W2168808956 @default.
• W2041535436 cites W2433682219 @default.
• W2041535436 cites W3174330282 @default.
• W2041535436 cites W4322384960 @default.
• W2041535436 doi "https://doi.org/10.1006/bbrc.2000.2832" @default.
• W2041535436 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10833460" @default.
• W2041535436 hasPublicationYear "2000" @default.
• W2041535436 type Work @default.
• W2041535436 sameAs 2041535436 @default.
• W2041535436 citedByCount "15" @default.
• W2041535436 countsByYear W20415354362014 @default.
• W2041535436 countsByYear W20415354362015 @default.
• W2041535436 countsByYear W20415354362016 @default.
• W2041535436 countsByYear W20415354362018 @default.
• W2041535436 countsByYear W20415354362019 @default.
• W2041535436 countsByYear W20415354362021 @default.
• W2041535436 crossrefType "journal-article" @default.
• W2041535436 hasAuthorship W2041535436A5033787859 @default.
• W2041535436 hasAuthorship W2041535436A5048774381 @default.
• W2041535436 hasAuthorship W2041535436A5049295113 @default.
• W2041535436 hasConcept C104292427 @default.
• W2041535436 hasConcept C104317684 @default.
• W2041535436 hasConcept C105580179 @default.
• W2041535436 hasConcept C116010114 @default.
• W2041535436 hasConcept C119113125 @default.
• W2041535436 hasConcept C153911025 @default.
• W2041535436 hasConcept C167625842 @default.
• W2041535436 hasConcept C187882448 @default.
• W2041535436 hasConcept C190472901 @default.
• W2041535436 hasConcept C204390595 @default.
• W2041535436 hasConcept C207230331 @default.
• W2041535436 hasConcept C36823959 @default.
• W2041535436 hasConcept C47289529 @default.
• W2041535436 hasConcept C52789158 @default.
• W2041535436 hasConcept C54355233 @default.
• W2041535436 hasConcept C83713313 @default.
• W2041535436 hasConcept C83730767 @default.
• W2041535436 hasConcept C86803240 @default.
• W2041535436 hasConcept C89604277 @default.
• W2041535436 hasConcept C94671646 @default.
• W2041535436 hasConceptScore W2041535436C104292427 @default.
• W2041535436 hasConceptScore W2041535436C104317684 @default.
• W2041535436 hasConceptScore W2041535436C105580179 @default.
• W2041535436 hasConceptScore W2041535436C116010114 @default.
• W2041535436 hasConceptScore W2041535436C119113125 @default.
• W2041535436 hasConceptScore W2041535436C153911025 @default.
• W2041535436 hasConceptScore W2041535436C167625842 @default.
• W2041535436 hasConceptScore W2041535436C187882448 @default.
• W2041535436 hasConceptScore W2041535436C190472901 @default.
• W2041535436 hasConceptScore W2041535436C204390595 @default.
• W2041535436 hasConceptScore W2041535436C207230331 @default.
• W2041535436 hasConceptScore W2041535436C36823959 @default.
• W2041535436 hasConceptScore W2041535436C47289529 @default.
• W2041535436 hasConceptScore W2041535436C52789158 @default.
• W2041535436 hasConceptScore W2041535436C54355233 @default.
• W2041535436 hasConceptScore W2041535436C83713313 @default.
• W2041535436 hasConceptScore W2041535436C83730767 @default.
• W2041535436 hasConceptScore W2041535436C86803240 @default.

• next