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• W2041556105 startingPage "9241" @default.
• W2041556105 abstract "Stimulation of the prefrontal cortex by acetylcholine is critical for attention; however, the cellular mechanisms underlying its influence on attention pathways within the brain are not well understood. Pyramidal neurons in layer VI of the prefrontal cortex are believed to play an important role in this process because they are excited by acetylcholine and provide a major source of feedback projections to the thalamus. Here, we show using whole-cell electrophysiology that the relatively rare alpha5 subunit of the nicotinic acetylcholine receptor powerfully enhances nicotinic currents in layer VI pyramidal neurons in prefrontal cortical brain slices from adult mice. In addition, behavioral experiments using the five-choice serial reaction time test show that the presence of the nicotinic receptor alpha5 subunit also increases the accuracy of adult mice on this visual attention task under highly demanding conditions. Together, these findings demonstrate a novel and important role for the nicotinic receptor alpha5 subunit in adult brain circuitry required for attentional performance." @default.
• W2041556105 created "2016-06-24" @default.
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• W2041556105 creator A5033903495 @default.
• W2041556105 creator A5047531759 @default.
• W2041556105 creator A5089699394 @default.
• W2041556105 date "2010-07-07" @default.
• W2041556105 modified "2023-10-13" @default.
• W2041556105 title "The Nicotinic Acetylcholine Receptor 5 Subunit Plays a Key Role in Attention Circuitry and Accuracy" @default.
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• W2041556105 cites W1840472544 @default.
• W2041556105 cites W1919808289 @default.
• W2041556105 cites W1968111834 @default.
• W2041556105 cites W1976309270 @default.
• W2041556105 cites W1978568586 @default.
• W2041556105 cites W1980643144 @default.
• W2041556105 cites W1985349781 @default.
• W2041556105 cites W1985422003 @default.
• W2041556105 cites W1986602349 @default.
• W2041556105 cites W1988797981 @default.
• W2041556105 cites W1991139008 @default.
• W2041556105 cites W1992556352 @default.
• W2041556105 cites W1994702360 @default.
• W2041556105 cites W1994905333 @default.
• W2041556105 cites W2001564330 @default.
• W2041556105 cites W2002151735 @default.
• W2041556105 cites W2002513166 @default.
• W2041556105 cites W2005497678 @default.
• W2041556105 cites W2005792445 @default.
• W2041556105 cites W2009558614 @default.
• W2041556105 cites W2010007267 @default.
• W2041556105 cites W2010375213 @default.
• W2041556105 cites W2013318053 @default.
• W2041556105 cites W2016159363 @default.
• W2041556105 cites W2016726321 @default.
• W2041556105 cites W2019159182 @default.
• W2041556105 cites W2022503151 @default.
• W2041556105 cites W2025739058 @default.
• W2041556105 cites W2026049415 @default.
• W2041556105 cites W2027606489 @default.
• W2041556105 cites W2028127185 @default.
• W2041556105 cites W2029743369 @default.
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• W2041556105 cites W2040527392 @default.
• W2041556105 cites W2041932465 @default.
• W2041556105 cites W2049324875 @default.
• W2041556105 cites W2055767347 @default.
• W2041556105 cites W2056998154 @default.
• W2041556105 cites W2057196462 @default.
• W2041556105 cites W2058517947 @default.
• W2041556105 cites W2059230386 @default.
• W2041556105 cites W2061475648 @default.
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• W2041556105 cites W2078385612 @default.
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• W2041556105 cites W2123133405 @default.
• W2041556105 cites W2124163128 @default.
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• W2041556105 cites W2128306943 @default.
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• W2041556105 cites W2134885683 @default.
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• W2041556105 cites W2139856187 @default.
• W2041556105 cites W2142268301 @default.
• W2041556105 cites W2143989432 @default.
• W2041556105 cites W2155986204 @default.
• W2041556105 cites W2156540685 @default.
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• W2041556105 doi "https://doi.org/10.1523/jneurosci.2258-10.2010" @default.
• W2041556105 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3004929" @default.
• W2041556105 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20610759" @default.
• W2041556105 hasPublicationYear "2010" @default.
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