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- W2041556817 abstract "Bacteria use type IV secretion systems (T4SS) to translocate macromolecular substrates destined for bacterial, plant or human target cells. The T4SS are medically important, contributing to virulence-gene spread, genome plasticity and the alteration of host cellular processes during infection. The T4SS are ancestrally related to bacterial conjugation machines, but present-day functions include (i) conjugal transfer of DNA by cell-to-cell contact, (ii) translocation of effector molecules to eukaryotic target cells, and (iii) DNA uptake from or release to the extracellular milieu. Rapid progress has been made toward identification of type IV secretion substrates and the requirements for substrate recognition." @default.
- W2041556817 created "2016-06-24" @default.
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- W2041556817 date "2003-11-01" @default.
- W2041556817 modified "2023-10-16" @default.
- W2041556817 title "The outs and ins of bacterial type IV secretion substrates" @default.
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- W2041556817 doi "https://doi.org/10.1016/j.tim.2003.09.004" @default.
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