FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2041606755> ?p ?o ?g. }

• W2041606755 endingPage "58" @default.
• W2041606755 startingPage "53" @default.
• W2041606755 abstract "Although recent studies have demonstrated prenatal nicotine can increase cardiovascular risk in the offspring, it is unknown whether exposure to nicotine during pregnancy also may be a risk for development of arrhythmia in the offspring. In addition, in previous studies of fetal arrhythmia affected by smoking, only two patterns, bradycardia and tachycardia, were observed. The present study examined acute effects of maternal nicotine on the fetal arrhythmia in utero, and chronic influence on offspring arrhythmia at adult stage following prenatal exposure to nicotine. Nicotine was administered to pregnant ewes and rats. In the fetal sheep, intravenous nicotine not only induced changes of fetal heart rate, but also caused cardiac cycle irregularity, single and multiple dropped cardiac cycles. Although maternal nicotine had no influence on fetal blood pH, lactic acid, hemocrit, Na+, K+ levels and plasma osmolality, fetal blood PO2 levels were significantly decreased following maternal nicotine in ewes. In offspring rats at 4–5 months after birth, prenatal exposure to nicotine significantly increased heart rate and premature ventricular contraction in restraint stress. In addition, arrhythmias induced by injection of nicotine were higher in the offspring prenatal exposure to nicotine in utero. The results provide new evidence that exposure to nicotine in pregnancy can cause fetal arrhythmia in various patterns besides tachycardia and bradycardia, the possible mechanisms for nicotine-induced fetal arrhythmia included in utero hypoxia. Importantly, following exposure to nicotine significantly increased risk of arrhythmia in the adult offspring. The finding offers new insight for development of cardiac rhythm problems in fetal origins. Copyright © 2009 John Wiley & Sons, Ltd." @default.
• W2041606755 created "2016-06-24" @default.
• W2041606755 creator A5038499684 @default.
• W2041606755 creator A5049755850 @default.
• W2041606755 creator A5059574029 @default.
• W2041606755 creator A5061952384 @default.
• W2041606755 creator A5062753537 @default.
• W2041606755 creator A5085910420 @default.
• W2041606755 creator A5088724529 @default.
• W2041606755 date "2010-01-01" @default.
• W2041606755 modified "2023-10-12" @default.
• W2041606755 title "Fetal and offspring arrhythmia following exposure to nicotine during pregnancy" @default.
• W2041606755 cites W123264792 @default.
• W2041606755 cites W1479892021 @default.
• W2041606755 cites W1988531373 @default.
• W2041606755 cites W1988697472 @default.
• W2041606755 cites W2000877041 @default.
• W2041606755 cites W2003813062 @default.
• W2041606755 cites W2011947382 @default.
• W2041606755 cites W2019823882 @default.
• W2041606755 cites W2026002815 @default.
• W2041606755 cites W2037051841 @default.
• W2041606755 cites W2041410896 @default.
• W2041606755 cites W2059128502 @default.
• W2041606755 cites W2066051529 @default.
• W2041606755 cites W2076626531 @default.
• W2041606755 cites W2081918088 @default.
• W2041606755 cites W2083795168 @default.
• W2041606755 cites W2097940040 @default.
• W2041606755 cites W2102589157 @default.
• W2041606755 cites W2105436590 @default.
• W2041606755 cites W2112547419 @default.
• W2041606755 cites W2116577137 @default.
• W2041606755 cites W2122045142 @default.
• W2041606755 cites W2122970163 @default.
• W2041606755 cites W2143058377 @default.
• W2041606755 cites W2145243943 @default.
• W2041606755 cites W2147328570 @default.
• W2041606755 cites W2154136495 @default.
• W2041606755 cites W2163580362 @default.
• W2041606755 cites W2169872809 @default.
• W2041606755 cites W247473604 @default.
• W2041606755 doi "https://doi.org/10.1002/jat.1471" @default.
• W2041606755 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19728315" @default.
• W2041606755 hasPublicationYear "2010" @default.
• W2041606755 type Work @default.
• W2041606755 sameAs 2041606755 @default.
• W2041606755 citedByCount "25" @default.
• W2041606755 countsByYear W20416067552012 @default.
• W2041606755 countsByYear W20416067552014 @default.
• W2041606755 countsByYear W20416067552015 @default.
• W2041606755 countsByYear W20416067552016 @default.
• W2041606755 countsByYear W20416067552017 @default.
• W2041606755 countsByYear W20416067552018 @default.
• W2041606755 countsByYear W20416067552019 @default.
• W2041606755 countsByYear W20416067552022 @default.
• W2041606755 countsByYear W20416067552023 @default.
• W2041606755 crossrefType "journal-article" @default.
• W2041606755 hasAuthorship W2041606755A5038499684 @default.
• W2041606755 hasAuthorship W2041606755A5049755850 @default.
• W2041606755 hasAuthorship W2041606755A5059574029 @default.
• W2041606755 hasAuthorship W2041606755A5061952384 @default.
• W2041606755 hasAuthorship W2041606755A5062753537 @default.
• W2041606755 hasAuthorship W2041606755A5085910420 @default.
• W2041606755 hasAuthorship W2041606755A5088724529 @default.
• W2041606755 hasConcept C112672928 @default.
• W2041606755 hasConcept C126322002 @default.
• W2041606755 hasConcept C134018914 @default.
• W2041606755 hasConcept C164705383 @default.
• W2041606755 hasConcept C172680121 @default.
• W2041606755 hasConcept C201614185 @default.
• W2041606755 hasConcept C2777495988 @default.
• W2041606755 hasConcept C2777953023 @default.
• W2041606755 hasConcept C2779161974 @default.
• W2041606755 hasConcept C2779234561 @default.
• W2041606755 hasConcept C2779547902 @default.
• W2041606755 hasConcept C2780283014 @default.
• W2041606755 hasConcept C2988455589 @default.
• W2041606755 hasConcept C42219234 @default.
• W2041606755 hasConcept C42407357 @default.
• W2041606755 hasConcept C54355233 @default.
• W2041606755 hasConcept C71924100 @default.
• W2041606755 hasConcept C84393581 @default.
• W2041606755 hasConcept C86803240 @default.
• W2041606755 hasConceptScore W2041606755C112672928 @default.
• W2041606755 hasConceptScore W2041606755C126322002 @default.
• W2041606755 hasConceptScore W2041606755C134018914 @default.
• W2041606755 hasConceptScore W2041606755C164705383 @default.
• W2041606755 hasConceptScore W2041606755C172680121 @default.
• W2041606755 hasConceptScore W2041606755C201614185 @default.
• W2041606755 hasConceptScore W2041606755C2777495988 @default.
• W2041606755 hasConceptScore W2041606755C2777953023 @default.
• W2041606755 hasConceptScore W2041606755C2779161974 @default.
• W2041606755 hasConceptScore W2041606755C2779234561 @default.
• W2041606755 hasConceptScore W2041606755C2779547902 @default.
• W2041606755 hasConceptScore W2041606755C2780283014 @default.
• W2041606755 hasConceptScore W2041606755C2988455589 @default.
• W2041606755 hasConceptScore W2041606755C42219234 @default.

• next