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• W2041608813 abstract "The lipid class composition of Semliki Forest virus grown in two clones of BHK21 cells was determined. The virus contained 0.41 mg of lipid per milligram of protein; of this 31% was neutral lipid, 61% phospholipid, and 8% glycolipid. The major neutral lipid was free cholesterol; the principal phospholipids were phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, and sphingomyelin. The major glycolipids were tentatively identified as sialolactosyl ceramides. The molar ratio of cholesterol to phospholipid was about 1. The lipids of Semliki Forest virus were similar to those of plasma membrane isolated from either infected or uninfected host cells. However, the virus contained much less free fatty acids and a little more cholesterol than the plasma membrane. The lipid composition of whole BHK21 cells and their endoplasmic reticulum differed clearly from that of the virus. In the virus there are about 10,000 cholesterol-phospholipid pairs, which can be arranged in a bilayer type of structure in the space available in the envelope." @default.
• W2041608813 created "2016-06-24" @default.
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• W2041608813 date "1971-11-01" @default.
• W2041608813 modified "2023-10-13" @default.
• W2041608813 title "The lipid class composition of Semliki Forest virus and of plasma membranes of the host cells" @default.
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• W2041608813 doi "https://doi.org/10.1016/0042-6822(71)90033-x" @default.
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