Matches in SemOpenAlex for { <https://semopenalex.org/work/W2041640076> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2041640076 endingPage "424" @default.
- W2041640076 startingPage "423" @default.
- W2041640076 abstract "Alternating chemoradiotherapy has recently been reported to produce encouraging results in patients with advanced head and neck cancer. We have treated 17 patients with squamous cell carcinoma of the upper esophagus by alternating chemoradiotherapy and by following the patients for 2 to 5 years, or until their death. Chemotherapy (cisplatin and 5-fluorouracil) was delivered during weeks 1, 4, and 7, and radiotherapy (180 to 200 cGy twice each day to 2,000 cGy) during weeks 2, 5, and 8 (total 6,000 cGy). Three patients (18%) died of toxicity (nadir sepsis). All 14 patients who survived the treatment achieved a complete response as shown by endoscopy and biopsy specimens, with restoration of swallowing, and none experienced a local relapse. Three patients died of distant metastases (actuarial incidence 32% at 3 years). The 5-year survival rate was only 16%, however, because 8 other patients with no evidence of the cancer died of a variety of other causes: radiation pneumonitis (1), chronic neutropenia (1), esophageal actinomycosis (1), pneumonia (2), stroke (1), myocardial infarction (1), and small-cell lung cancer (1). Conceivably, some further improvement in the results might occur from cytokines, stem cells, and brachytherapy (by decreasing deaths due to toxicity), but with so many causes of comorbidity it seems unlikely, for the foreseeable future, that the 5-year survival rate could be much improved by better treatment of esophageal cancer." @default.
- W2041640076 created "2016-06-24" @default.
- W2041640076 creator A5031075467 @default.
- W2041640076 creator A5047450557 @default.
- W2041640076 creator A5060079446 @default.
- W2041640076 creator A5082068552 @default.
- W2041640076 date "1994-11-01" @default.
- W2041640076 modified "2023-10-16" @default.
- W2041640076 title "Patterns of failure in carcinoma of the upper esophagus after alternating chemoradiotherapy" @default.
- W2041640076 cites W1985492920 @default.
- W2041640076 cites W1986884101 @default.
- W2041640076 cites W2005652111 @default.
- W2041640076 cites W2049193446 @default.
- W2041640076 cites W2129039105 @default.
- W2041640076 cites W2172825007 @default.
- W2041640076 cites W2290090610 @default.
- W2041640076 cites W2074981112 @default.
- W2041640076 doi "https://doi.org/10.1016/s0002-9610(05)80090-x" @default.
- W2041640076 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7977965" @default.
- W2041640076 hasPublicationYear "1994" @default.
- W2041640076 type Work @default.
- W2041640076 sameAs 2041640076 @default.
- W2041640076 citedByCount "9" @default.
- W2041640076 countsByYear W20416400762013 @default.
- W2041640076 crossrefType "journal-article" @default.
- W2041640076 hasAuthorship W2041640076A5031075467 @default.
- W2041640076 hasAuthorship W2041640076A5047450557 @default.
- W2041640076 hasAuthorship W2041640076A5060079446 @default.
- W2041640076 hasAuthorship W2041640076A5082068552 @default.
- W2041640076 hasConcept C121608353 @default.
- W2041640076 hasConcept C126322002 @default.
- W2041640076 hasConcept C141071460 @default.
- W2041640076 hasConcept C2777546739 @default.
- W2041640076 hasConcept C2777819096 @default.
- W2041640076 hasConcept C2778424827 @default.
- W2041640076 hasConcept C2779134260 @default.
- W2041640076 hasConcept C2779920096 @default.
- W2041640076 hasConcept C2780596822 @default.
- W2041640076 hasConcept C43270747 @default.
- W2041640076 hasConcept C509974204 @default.
- W2041640076 hasConcept C71924100 @default.
- W2041640076 hasConcept C90924648 @default.
- W2041640076 hasConceptScore W2041640076C121608353 @default.
- W2041640076 hasConceptScore W2041640076C126322002 @default.
- W2041640076 hasConceptScore W2041640076C141071460 @default.
- W2041640076 hasConceptScore W2041640076C2777546739 @default.
- W2041640076 hasConceptScore W2041640076C2777819096 @default.
- W2041640076 hasConceptScore W2041640076C2778424827 @default.
- W2041640076 hasConceptScore W2041640076C2779134260 @default.
- W2041640076 hasConceptScore W2041640076C2779920096 @default.
- W2041640076 hasConceptScore W2041640076C2780596822 @default.
- W2041640076 hasConceptScore W2041640076C43270747 @default.
- W2041640076 hasConceptScore W2041640076C509974204 @default.
- W2041640076 hasConceptScore W2041640076C71924100 @default.
- W2041640076 hasConceptScore W2041640076C90924648 @default.
- W2041640076 hasIssue "5" @default.
- W2041640076 hasLocation W20416400761 @default.
- W2041640076 hasLocation W20416400762 @default.
- W2041640076 hasOpenAccess W2041640076 @default.
- W2041640076 hasPrimaryLocation W20416400761 @default.
- W2041640076 hasRelatedWork W2014435840 @default.
- W2041640076 hasRelatedWork W2017705908 @default.
- W2041640076 hasRelatedWork W2052339117 @default.
- W2041640076 hasRelatedWork W2053036048 @default.
- W2041640076 hasRelatedWork W2056156526 @default.
- W2041640076 hasRelatedWork W2115407619 @default.
- W2041640076 hasRelatedWork W2390802711 @default.
- W2041640076 hasRelatedWork W2415260940 @default.
- W2041640076 hasRelatedWork W2417724419 @default.
- W2041640076 hasRelatedWork W4285096213 @default.
- W2041640076 hasVolume "168" @default.
- W2041640076 isParatext "false" @default.
- W2041640076 isRetracted "false" @default.
- W2041640076 magId "2041640076" @default.
- W2041640076 workType "article" @default.