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- W2041650982 abstract "Using recombinant human tau protein phosphorylated by a brain extract and the glycogen synthase kinase-3β in the absence or the presence of heparin, we showed that phosphorylation-dependent antibody AD2 recognition only requires phosphorylated Ser-396. By the Spot multiple peptide synthesis method, we showed that Tyr-394, SerP-396 and Pro-397 are critical for AD2 binding. A decrease in the binding of AD2 was observed with increasing phosphorylation of residues in the vicinity of SerP-396." @default.
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- W2041650982 date "2000-05-01" @default.
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- W2041650982 title "Binding specificity of monoclonal antibody AD2: influence of the phosphorylation state of tau" @default.
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- W2041650982 doi "https://doi.org/10.1016/s0169-328x(00)00073-5" @default.
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