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- W2041651168 abstract "The ability to autoregulate blood flow in the extracorporeal membrane oxygenation (ECMO) circuit is critical to prevent cavitation and air embolism. Conventional circuits have used a spring-loaded mechanical switching device that interrupts the flow of power to the roller head when falling venous return collapses the venous bladder. This device has been less than desirable due to being poorly adjustable, subject to sporadic flow in periods of hypovolemia, and not commercially avialable. An improved alternative is reported using a commercially available pressure monitor and computerized switching device, which, when attached to the venous reservoir or bladder, has the ability to autoregulate blood flow in the ECMO circuit by smoothly regulating the roller head velocity. Experience with this system in the laboratory employing a swine model, and in 35 infants, is reported without device-related complications. The ability to autoregulate blood flow in the extracorporeal membrane oxygenation (ECMO) circuit is critical to prevent cavitation and air embolism. Conventional circuits have used a spring-loaded mechanical switching device that interrupts the flow of power to the roller head when falling venous return collapses the venous bladder. This device has been less than desirable due to being poorly adjustable, subject to sporadic flow in periods of hypovolemia, and not commercially avialable. An improved alternative is reported using a commercially available pressure monitor and computerized switching device, which, when attached to the venous reservoir or bladder, has the ability to autoregulate blood flow in the ECMO circuit by smoothly regulating the roller head velocity. Experience with this system in the laboratory employing a swine model, and in 35 infants, is reported without device-related complications." @default.
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- W2041651168 date "1989-03-01" @default.
- W2041651168 modified "2023-10-14" @default.
- W2041651168 title "A simplified method for autoregulation of blood flow in the extracorporeal membrane oxygenation circuit" @default.
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- W2041651168 doi "https://doi.org/10.1016/s0022-3468(89)80005-3" @default.
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