FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2041660810> ?p ?o ?g. }

• W2041660810 endingPage "95" @default.
• W2041660810 startingPage "91" @default.
• W2041660810 abstract "The frequency and significance of p53 alterations in cutaneous melanoma have not been completely clarified. In the present study, 31 primary melanomas of the nodular type and 15 metastases occurring between 1981 and 1983 were studied with respect to mutations in exons 7 and 8, as well as to p53 protein immunostaining using different antibodies. Altogether 13% of the primary tumors showed strong p53 staining using the DO-7 antibody. Different results were obtained with other antibodies. Seven mutations were found in primary and metastatic tumors; all of these were single base changes, most of which occurred in the core domain of the p53 protein responsible for sequence-specific DNA binding (residues 102–293). The mutations were not significantly associated with p53 staining results, and p53 alterations (mutations or marked immunopositivity) had no prognostic value. Our results indicate that point mutations in exons 7 and 8 are more frequent than previously reported in primary melanomas, and such changes may be important for the development of certain melanoma subgroups. Int. J. Cancer (Pred. Oncol.) 79:91–95, 1998. © 1998 Wiley-Liss, Inc." @default.
• W2041660810 created "2016-06-24" @default.
• W2041660810 creator A5013109928 @default.
• W2041660810 creator A5022110525 @default.
• W2041660810 creator A5066573040 @default.
• W2041660810 creator A5068445062 @default.
• W2041660810 creator A5085162697 @default.
• W2041660810 date "1998-02-20" @default.
• W2041660810 modified "2023-10-18" @default.
• W2041660810 title "Frequent mutations of the p53 gene in cutaneous melanoma of the nodular type" @default.
• W2041660810 cites W1965573334 @default.
• W2041660810 cites W1967475743 @default.
• W2041660810 cites W1967629365 @default.
• W2041660810 cites W1970910072 @default.
• W2041660810 cites W1987783969 @default.
• W2041660810 cites W1988121733 @default.
• W2041660810 cites W1988907198 @default.
• W2041660810 cites W1998280377 @default.
• W2041660810 cites W2016107093 @default.
• W2041660810 cites W2016508329 @default.
• W2041660810 cites W2021482519 @default.
• W2041660810 cites W2022122800 @default.
• W2041660810 cites W2042316019 @default.
• W2041660810 cites W2048740077 @default.
• W2041660810 cites W2062110812 @default.
• W2041660810 cites W2081661161 @default.
• W2041660810 cites W2089412568 @default.
• W2041660810 cites W2090157013 @default.
• W2041660810 cites W2096276671 @default.
• W2041660810 cites W2099907467 @default.
• W2041660810 cites W2150097377 @default.
• W2041660810 cites W2165331184 @default.
• W2041660810 doi "https://doi.org/10.1002/(sici)1097-0215(19980220)79:1<91::aid-ijc17>3.0.co;2-k" @default.
• W2041660810 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9495365" @default.
• W2041660810 hasPublicationYear "1998" @default.
• W2041660810 type Work @default.
• W2041660810 sameAs 2041660810 @default.
• W2041660810 citedByCount "42" @default.
• W2041660810 countsByYear W20416608102016 @default.
• W2041660810 countsByYear W20416608102019 @default.
• W2041660810 countsByYear W20416608102021 @default.
• W2041660810 crossrefType "journal-article" @default.
• W2041660810 hasAuthorship W2041660810A5013109928 @default.
• W2041660810 hasAuthorship W2041660810A5022110525 @default.
• W2041660810 hasAuthorship W2041660810A5066573040 @default.
• W2041660810 hasAuthorship W2041660810A5068445062 @default.
• W2041660810 hasAuthorship W2041660810A5085162697 @default.
• W2041660810 hasBestOaLocation W20416608101 @default.
• W2041660810 hasConcept C104317684 @default.
• W2041660810 hasConcept C121608353 @default.
• W2041660810 hasConcept C142724271 @default.
• W2041660810 hasConcept C153911025 @default.
• W2041660810 hasConcept C159654299 @default.
• W2041660810 hasConcept C176944494 @default.
• W2041660810 hasConcept C204232928 @default.
• W2041660810 hasConcept C2777658100 @default.
• W2041660810 hasConcept C36823959 @default.
• W2041660810 hasConcept C4224716 @default.
• W2041660810 hasConcept C501734568 @default.
• W2041660810 hasConcept C502942594 @default.
• W2041660810 hasConcept C54355233 @default.
• W2041660810 hasConcept C71924100 @default.
• W2041660810 hasConcept C74864618 @default.
• W2041660810 hasConcept C86803240 @default.
• W2041660810 hasConceptScore W2041660810C104317684 @default.
• W2041660810 hasConceptScore W2041660810C121608353 @default.
• W2041660810 hasConceptScore W2041660810C142724271 @default.
• W2041660810 hasConceptScore W2041660810C153911025 @default.
• W2041660810 hasConceptScore W2041660810C159654299 @default.
• W2041660810 hasConceptScore W2041660810C176944494 @default.
• W2041660810 hasConceptScore W2041660810C204232928 @default.
• W2041660810 hasConceptScore W2041660810C2777658100 @default.
• W2041660810 hasConceptScore W2041660810C36823959 @default.
• W2041660810 hasConceptScore W2041660810C4224716 @default.
• W2041660810 hasConceptScore W2041660810C501734568 @default.
• W2041660810 hasConceptScore W2041660810C502942594 @default.
• W2041660810 hasConceptScore W2041660810C54355233 @default.
• W2041660810 hasConceptScore W2041660810C71924100 @default.
• W2041660810 hasConceptScore W2041660810C74864618 @default.
• W2041660810 hasConceptScore W2041660810C86803240 @default.
• W2041660810 hasIssue "1" @default.
• W2041660810 hasLocation W20416608101 @default.
• W2041660810 hasLocation W20416608102 @default.
• W2041660810 hasOpenAccess W2041660810 @default.
• W2041660810 hasPrimaryLocation W20416608101 @default.
• W2041660810 hasRelatedWork W1979893467 @default.
• W2041660810 hasRelatedWork W2042848525 @default.
• W2041660810 hasRelatedWork W2078228152 @default.
• W2041660810 hasRelatedWork W2242689536 @default.
• W2041660810 hasRelatedWork W2388007221 @default.
• W2041660810 hasRelatedWork W2395037589 @default.
• W2041660810 hasRelatedWork W2413359840 @default.
• W2041660810 hasRelatedWork W2429203605 @default.
• W2041660810 hasRelatedWork W4238619026 @default.
• W2041660810 hasRelatedWork W68975081 @default.
• W2041660810 hasVolume "79" @default.
• W2041660810 isParatext "false" @default.
• W2041660810 isRetracted "false" @default.

• next