FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2041683238> ?p ?o ?g. }

• W2041683238 endingPage "11" @default.
• W2041683238 startingPage "3" @default.
• W2041683238 abstract "Evaluar el impacto sanitario y económico en España de la implementación de la vacunación frente al virus del papiloma humano (VPH) tipos 6, 11, 16 y 18 en una cohorte de adolescentes, junto a la estrategia de cribado existente. Se ha adaptado al contexto español un modelo de Markov de la historia natural de la infección por VPH, que incluía cribado y vacunación. Se comparó la nueva estrategia (añadir la vacuna frente a VPH 6, 11, 16 y 18, administrada a una cohorte de niñas de 11 años de edad con una cobertura del 80%, a los sistemas de cribado actuales) con la estrategia de cribado existente. El análisis se realizó según la perspectiva del sistema sanitario y sólo incluyó costes directos. El coste incremental por año de vida ganado (AVG) y por año de vida ganado ajustado por calidad (AVAC) de la introducción de la vacuna frente al VPH, junto a los programas actuales de cribado, en España fue de 8.657 € y 6.493 €, respectivamente. Los análisis de sensibilidad demostraron que la relación coste-efectividad es estable, pero sensible a la tasa de descuento utilizada para los costes y beneficios. La estrategia de añadir la vacuna tetravalente frente a VPH 6, 11, 16 y 18, administrada a las niñas de 11 años de edad, a los programas actuales de cribado es una estrategia eficiente en la reducción de la carga que representa el cáncer cervical, las lesiones precancerosas y las verrugas genitales en España. A vaccine to prevent diseases due to human papillomavirus (HPV) types 6, 11, 16 and 18 is now available in Spain. The objective of this study was to assess the health and economic impact in Spain of implementing a four-valent HPV vaccine alongside existing screening versus screening alone. A Markov model of the natural history of HPV infection, incorporating screening and vaccination, was adapted to the Spanish context. A vaccine that would prevent 100% of HPV 6, 11, 16 and 18-associated diseases, with a lifetime duration and 80% coverage, given to girls at age 11 plus current screening was compared to screening alone. The analysis was made from the third-party payer perspective and therefore excluded indirect costs such as loss of productivity. The incremental cost per life years gained (LYG) and per quality-adjusted life years (QALY) gained for the introduction of HPV vaccination alongside the Spanish cervical cancer screening programme was 8,657 € and 6,493 €, respectively. Sensitivity analyses demonstrated that the cost-effectiveness was stable, but was most sensitive to the discount rate used for costs and benefits. These analyses demonstrate that adding a four-valent HPV vaccine to the current screening programme in Spain is a cost-effective strategy for reducing the burden of cervical cancer, pre-cancerous lesions and genital warts." @default.
• W2041683238 created "2016-06-24" @default.
• W2041683238 creator A5018963228 @default.
• W2041683238 creator A5034715948 @default.
• W2041683238 creator A5047568162 @default.
• W2041683238 creator A5049696840 @default.
• W2041683238 creator A5079476800 @default.
• W2041683238 creator A5085019074 @default.
• W2041683238 date "2008-01-01" @default.
• W2041683238 modified "2023-09-24" @default.
• W2041683238 title "Análisis de coste-efectividad de la vacunación frente al virus del papiloma humano tipos 6, 11, 16 y 18 en España" @default.
• W2041683238 cites W1982987943 @default.
• W2041683238 cites W1992519297 @default.
• W2041683238 cites W2004695854 @default.
• W2041683238 cites W2007193922 @default.
• W2041683238 cites W2013020348 @default.
• W2041683238 cites W2018413784 @default.
• W2041683238 cites W2029057114 @default.
• W2041683238 cites W2031923021 @default.
• W2041683238 cites W2040206375 @default.
• W2041683238 cites W2063525217 @default.
• W2041683238 cites W2066860562 @default.
• W2041683238 cites W2077666724 @default.
• W2041683238 cites W2089454110 @default.
• W2041683238 cites W2094581205 @default.
• W2041683238 cites W2112846077 @default.
• W2041683238 cites W2113839478 @default.
• W2041683238 cites W2126246455 @default.
• W2041683238 cites W2127043059 @default.
• W2041683238 cites W2129650487 @default.
• W2041683238 cites W2130036154 @default.
• W2041683238 cites W2136405573 @default.
• W2041683238 cites W2138983746 @default.
• W2041683238 cites W2151780198 @default.
• W2041683238 cites W2153257909 @default.
• W2041683238 cites W2155105463 @default.
• W2041683238 cites W2166632132 @default.
• W2041683238 cites W2169228839 @default.
• W2041683238 cites W86337090 @default.
• W2041683238 doi "https://doi.org/10.1016/s1576-9887(08)71915-0" @default.
• W2041683238 hasPublicationYear "2008" @default.
• W2041683238 type Work @default.
• W2041683238 sameAs 2041683238 @default.
• W2041683238 citedByCount "12" @default.
• W2041683238 countsByYear W20416832382012 @default.
• W2041683238 countsByYear W20416832382013 @default.
• W2041683238 countsByYear W20416832382014 @default.
• W2041683238 countsByYear W20416832382015 @default.
• W2041683238 crossrefType "journal-article" @default.
• W2041683238 hasAuthorship W2041683238A5018963228 @default.
• W2041683238 hasAuthorship W2041683238A5034715948 @default.
• W2041683238 hasAuthorship W2041683238A5047568162 @default.
• W2041683238 hasAuthorship W2041683238A5049696840 @default.
• W2041683238 hasAuthorship W2041683238A5079476800 @default.
• W2041683238 hasAuthorship W2041683238A5085019074 @default.
• W2041683238 hasConcept C142362112 @default.
• W2041683238 hasConcept C15708023 @default.
• W2041683238 hasConcept C71924100 @default.
• W2041683238 hasConceptScore W2041683238C142362112 @default.
• W2041683238 hasConceptScore W2041683238C15708023 @default.
• W2041683238 hasConceptScore W2041683238C71924100 @default.
• W2041683238 hasIssue "1" @default.
• W2041683238 hasLocation W20416832381 @default.
• W2041683238 hasOpenAccess W2041683238 @default.
• W2041683238 hasPrimaryLocation W20416832381 @default.
• W2041683238 hasRelatedWork W1506200166 @default.
• W2041683238 hasRelatedWork W1995515455 @default.
• W2041683238 hasRelatedWork W2039318446 @default.
• W2041683238 hasRelatedWork W2048182022 @default.
• W2041683238 hasRelatedWork W2080531066 @default.
• W2041683238 hasRelatedWork W2604872355 @default.
• W2041683238 hasRelatedWork W2748952813 @default.
• W2041683238 hasRelatedWork W2899084033 @default.
• W2041683238 hasRelatedWork W3032375762 @default.
• W2041683238 hasRelatedWork W3108674512 @default.
• W2041683238 hasVolume "9" @default.
• W2041683238 isParatext "false" @default.
• W2041683238 isRetracted "false" @default.
• W2041683238 magId "2041683238" @default.
• W2041683238 workType "article" @default.