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• W2041736213 abstract "Epilepsy recently has been defined conceptually as a condition of at least one seizure, with an enduring predisposition to have seizures. It is not yet clear how to make this definition operational and practical. A diagnosis of epilepsy has potentially serious consequences for health, psychosocial well-being, and economics, and, therefore, it should be made with a high level of certainty. A definite diagnosis of epilepsy can be made with two unprovoked seizures at least 24 h apart. This method has the benefit of simplicity and consistency with past epidemiologic studies. Nevertheless, certain circumstances suggest a high likelihood of having a second seizure, as evidenced by common clinical practice of considering treatment after a first unprovoked seizure in conjunction with additional risk factors (surrogate markers). One unifying approach is an operational definition of definite epilepsy after two unprovoked seizures at least 24 h apart. An operational definition of probable epilepsy can be established with one unprovoked seizure and clinical, electroencephalography (EEG), neuroimaging, genetic, or other information to suggest greater than a 50% chance of having another seizure. Possible epilepsy operationally would exist with a single unprovoked seizure and insufficient evidence to predict a high likelihood of recurrence. Future clinical and epidemiologic evidence would allow refinements of the operational definitions." @default.
• W2041736213 created "2016-06-24" @default.
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• W2041736213 date "2008-12-01" @default.
• W2041736213 modified "2023-09-23" @default.
• W2041736213 title "Debate: When does a seizure imply epilepsy?" @default.
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• W2041736213 doi "https://doi.org/10.1111/j.1528-1167.2008.01921.x" @default.
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