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• W2041825034 abstract "Critical limb ischemia (CLI), the most advanced form of peripheral artery disease (PAD), carries grave implications with regard to morbidity and mortality. Within 1 year of CLI diagnosis, 40% to 50% of diabetics will experience an amputation, and 20% to 25% will die. Management is optimally directed at increasing blood flow to the affected extremity to relieve rest pain, heal ischemic ulcerations , avoid limb loss, and prevent cardiovascular events. This management is achieved by guideline-directed medical therapy and risk factor modification, whereas the mainstay of therapy remains revascularization by endovascular or surgical means for patients who are deemed potential candidates." @default.
• W2041825034 created "2016-06-24" @default.
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• W2041825034 date "2015-02-01" @default.
• W2041825034 modified "2023-09-26" @default.
• W2041825034 title "Critical Limb Ischemia" @default.
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• W2041825034 doi "https://doi.org/10.1016/j.ccl.2014.09.008" @default.
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