Matches in SemOpenAlex for { <https://semopenalex.org/work/W2041840159> ?p ?o ?g. }
- W2041840159 endingPage "8" @default.
- W2041840159 startingPage "1" @default.
- W2041840159 abstract "The identification of Runx2 (runt-related protein 2) function has greatly advanced the understanding of skeletal development over the last 5 years. Runx2 is regulated transcriptionally and post-translationally through the activity of many identified factors, although, the physiological significance of each remains to be demonstrated. The interaction of Runx2 with other transcription factors and cofactors has been shown to be important in Runx2-dependent gene regulation. Runx2 plays important roles in multiple steps of skeletal development. Runx2 determines the lineage of osteoblasts from multipotent mesenchymal cells, enhances osteoblast differentiation at an early stage, and inhibits osteoblast differentiation at a late stage. Runx2 plays crucial roles in chondrocyte maturation and in the specification of cartilage phenotypes. Furthermore, Runx2 is involved in vascular invasion into cartilage and osteoclastogenesis. Therefore, the determination of Runx2 function and the investigation of the cascades of Runx2-dependent gene regulation are important in the elucidation of skeletal biology." @default.
- W2041840159 created "2016-06-24" @default.
- W2041840159 creator A5010742020 @default.
- W2041840159 date "2002-01-01" @default.
- W2041840159 modified "2023-10-18" @default.
- W2041840159 title "Runx2, A multifunctional transcription factor in skeletal development" @default.
- W2041840159 cites W1917301047 @default.
- W2041840159 cites W1965698106 @default.
- W2041840159 cites W1971017689 @default.
- W2041840159 cites W1973613153 @default.
- W2041840159 cites W1982627750 @default.
- W2041840159 cites W1989533590 @default.
- W2041840159 cites W1992184028 @default.
- W2041840159 cites W1994596418 @default.
- W2041840159 cites W1997717120 @default.
- W2041840159 cites W1997812904 @default.
- W2041840159 cites W1999032828 @default.
- W2041840159 cites W1999538067 @default.
- W2041840159 cites W2006291181 @default.
- W2041840159 cites W2010048745 @default.
- W2041840159 cites W2013714561 @default.
- W2041840159 cites W2025046506 @default.
- W2041840159 cites W2034023141 @default.
- W2041840159 cites W2036287488 @default.
- W2041840159 cites W2040814514 @default.
- W2041840159 cites W2042839797 @default.
- W2041840159 cites W2055673006 @default.
- W2041840159 cites W2058139610 @default.
- W2041840159 cites W2066504997 @default.
- W2041840159 cites W2067573703 @default.
- W2041840159 cites W2070591061 @default.
- W2041840159 cites W2070793437 @default.
- W2041840159 cites W2079475603 @default.
- W2041840159 cites W2079985291 @default.
- W2041840159 cites W2083319499 @default.
- W2041840159 cites W2084776852 @default.
- W2041840159 cites W2085425025 @default.
- W2041840159 cites W2085627522 @default.
- W2041840159 cites W2088215231 @default.
- W2041840159 cites W2089350528 @default.
- W2041840159 cites W2090807626 @default.
- W2041840159 cites W2098326006 @default.
- W2041840159 cites W2102059629 @default.
- W2041840159 cites W2103012849 @default.
- W2041840159 cites W2119173715 @default.
- W2041840159 cites W2121551386 @default.
- W2041840159 cites W2122367477 @default.
- W2041840159 cites W2130671879 @default.
- W2041840159 cites W2134678935 @default.
- W2041840159 cites W2137298996 @default.
- W2041840159 cites W2158018007 @default.
- W2041840159 cites W2159868431 @default.
- W2041840159 cites W2163995267 @default.
- W2041840159 cites W2171604853 @default.
- W2041840159 cites W2186400656 @default.
- W2041840159 cites W2401164797 @default.
- W2041840159 cites W4381243263 @default.
- W2041840159 doi "https://doi.org/10.1002/jcb.10276" @default.
- W2041840159 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12210716" @default.
- W2041840159 hasPublicationYear "2002" @default.
- W2041840159 type Work @default.
- W2041840159 sameAs 2041840159 @default.
- W2041840159 citedByCount "284" @default.
- W2041840159 countsByYear W20418401592012 @default.
- W2041840159 countsByYear W20418401592013 @default.
- W2041840159 countsByYear W20418401592014 @default.
- W2041840159 countsByYear W20418401592015 @default.
- W2041840159 countsByYear W20418401592016 @default.
- W2041840159 countsByYear W20418401592017 @default.
- W2041840159 countsByYear W20418401592018 @default.
- W2041840159 countsByYear W20418401592019 @default.
- W2041840159 countsByYear W20418401592020 @default.
- W2041840159 countsByYear W20418401592021 @default.
- W2041840159 countsByYear W20418401592022 @default.
- W2041840159 countsByYear W20418401592023 @default.
- W2041840159 crossrefType "journal-article" @default.
- W2041840159 hasAuthorship W2041840159A5010742020 @default.
- W2041840159 hasConcept C104317684 @default.
- W2041840159 hasConcept C105702510 @default.
- W2041840159 hasConcept C198826908 @default.
- W2041840159 hasConcept C202751555 @default.
- W2041840159 hasConcept C2776363554 @default.
- W2041840159 hasConcept C2778260815 @default.
- W2041840159 hasConcept C2780550940 @default.
- W2041840159 hasConcept C2781403057 @default.
- W2041840159 hasConcept C54355233 @default.
- W2041840159 hasConcept C86339819 @default.
- W2041840159 hasConcept C86803240 @default.
- W2041840159 hasConcept C95444343 @default.
- W2041840159 hasConceptScore W2041840159C104317684 @default.
- W2041840159 hasConceptScore W2041840159C105702510 @default.
- W2041840159 hasConceptScore W2041840159C198826908 @default.
- W2041840159 hasConceptScore W2041840159C202751555 @default.
- W2041840159 hasConceptScore W2041840159C2776363554 @default.
- W2041840159 hasConceptScore W2041840159C2778260815 @default.
- W2041840159 hasConceptScore W2041840159C2780550940 @default.
- W2041840159 hasConceptScore W2041840159C2781403057 @default.
- W2041840159 hasConceptScore W2041840159C54355233 @default.