FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2041855785> ?p ?o ?g. }

• W2041855785 endingPage "119" @default.
• W2041855785 startingPage "114" @default.
• W2041855785 abstract "The syndrome of delayed toxic–hypoxic encephalopathy is triggered by a sedating toxin that precipitates a period of cerebral hypoxaemia. The syndrome is rare and has a classic biphasic course with a seemingly complete recovery from the first episode of coma followed by a dramatic deterioration. We describe the diagnostic challenge provided by such a case.Day 1 : A 37-year-old man took 30 ml of methadone, 150 mg diazepam, plus cannabis and alcohol. On waking the next day, he took 20 ml more methadone and spent the afternoon and evening watching DVDs. The following morning, he rose at midday before returning to bed, where his partner found him unrousable at 22:00. He was taken to the emergency department where his Glasgow Coma Score was 3/15 and he had small pupils (see figure 1, time line). On arrival he was hypoxic, tachycardic and hypotensive. Blood tests showed acute renal impairment, hyperkalaemia, with serum creatine kinase of >8000 U/l (24–195) and hypoglycaemia. His blood biochemistry was corrected and two doses of naloxone given to no effect. A CT scan of head was normal. Toxicology screen was positive for methadone, benzodiazepines and cannabinoids. Blood-borne viral serology was negative. He was intubated and spent 4 days in intensive care; on extubation he was confused and paranoid but was discharged after 10 days in hospital ( day 12 ), ‘99% back to normal’.Figure 1 Time line depicting the patient's clinical status.Seventeen days after discharge ( day 28 ), he lost the ability to walk and was doubly incontinent; 38 days after the initial toxic insult he was re-admitted to hospital. On examination, he had reduced facial expression, spoke words but not full sentences and followed simple commands. He had marked action and rest myoclonus (video 1), with bradykinesia in the upper limbs and hypereflexia. An MR scan of brain (figure 2) showed extensive diffuse, symmetrical …" @default.
• W2041855785 created "2016-06-24" @default.
• W2041855785 creator A5026621001 @default.
• W2041855785 creator A5040064830 @default.
• W2041855785 creator A5040166835 @default.
• W2041855785 creator A5052152168 @default.
• W2041855785 creator A5068261023 @default.
• W2041855785 date "2013-03-06" @default.
• W2041855785 modified "2023-10-17" @default.
• W2041855785 title "Delayed toxic–hypoxic encephalopathy" @default.
• W2041855785 cites W1668187395 @default.
• W2041855785 cites W1764247516 @default.
• W2041855785 cites W1967946331 @default.
• W2041855785 cites W2021326034 @default.
• W2041855785 cites W2044360059 @default.
• W2041855785 cites W2063607615 @default.
• W2041855785 cites W2085387744 @default.
• W2041855785 cites W2101112453 @default.
• W2041855785 cites W2113290574 @default.
• W2041855785 cites W2130555128 @default.
• W2041855785 cites W2131038314 @default.
• W2041855785 cites W2136019899 @default.
• W2041855785 cites W2137428916 @default.
• W2041855785 cites W2148399486 @default.
• W2041855785 cites W2169073139 @default.
• W2041855785 doi "https://doi.org/10.1136/practneurol-2012-000402" @default.
• W2041855785 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23468562" @default.
• W2041855785 hasPublicationYear "2013" @default.
• W2041855785 type Work @default.
• W2041855785 sameAs 2041855785 @default.
• W2041855785 citedByCount "6" @default.
• W2041855785 countsByYear W20418557852014 @default.
• W2041855785 countsByYear W20418557852018 @default.
• W2041855785 countsByYear W20418557852019 @default.
• W2041855785 crossrefType "journal-article" @default.
• W2041855785 hasAuthorship W2041855785A5026621001 @default.
• W2041855785 hasAuthorship W2041855785A5040064830 @default.
• W2041855785 hasAuthorship W2041855785A5040166835 @default.
• W2041855785 hasAuthorship W2041855785A5052152168 @default.
• W2041855785 hasAuthorship W2041855785A5068261023 @default.
• W2041855785 hasConcept C118552586 @default.
• W2041855785 hasConcept C177713679 @default.
• W2041855785 hasConcept C178790620 @default.
• W2041855785 hasConcept C185592680 @default.
• W2041855785 hasConcept C2777257487 @default.
• W2041855785 hasConcept C2778621155 @default.
• W2041855785 hasConcept C540031477 @default.
• W2041855785 hasConcept C71924100 @default.
• W2041855785 hasConcept C7836513 @default.
• W2041855785 hasConceptScore W2041855785C118552586 @default.
• W2041855785 hasConceptScore W2041855785C177713679 @default.
• W2041855785 hasConceptScore W2041855785C178790620 @default.
• W2041855785 hasConceptScore W2041855785C185592680 @default.
• W2041855785 hasConceptScore W2041855785C2777257487 @default.
• W2041855785 hasConceptScore W2041855785C2778621155 @default.
• W2041855785 hasConceptScore W2041855785C540031477 @default.
• W2041855785 hasConceptScore W2041855785C71924100 @default.
• W2041855785 hasConceptScore W2041855785C7836513 @default.
• W2041855785 hasIssue "2" @default.
• W2041855785 hasLocation W20418557851 @default.
• W2041855785 hasLocation W20418557852 @default.
• W2041855785 hasOpenAccess W2041855785 @default.
• W2041855785 hasPrimaryLocation W20418557851 @default.
• W2041855785 hasRelatedWork W2050968799 @default.
• W2041855785 hasRelatedWork W2061022229 @default.
• W2041855785 hasRelatedWork W2371533146 @default.
• W2041855785 hasRelatedWork W2414317945 @default.
• W2041855785 hasRelatedWork W3119898309 @default.
• W2041855785 hasRelatedWork W3120238020 @default.
• W2041855785 hasRelatedWork W4211211826 @default.
• W2041855785 hasRelatedWork W4235102493 @default.
• W2041855785 hasRelatedWork W4237934984 @default.
• W2041855785 hasRelatedWork W4252371801 @default.
• W2041855785 hasVolume "13" @default.
• W2041855785 isParatext "false" @default.
• W2041855785 isRetracted "false" @default.
• W2041855785 magId "2041855785" @default.
• W2041855785 workType "article" @default.