Matches in SemOpenAlex for { <https://semopenalex.org/work/W2041938891> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2041938891 endingPage "192" @default.
- W2041938891 startingPage "185" @default.
- W2041938891 abstract "This study determined whether twice-daily intrauterine injections of ovine conceptus secretory proteins (oCSP) containing type-I trophoblast interferon (25 micrograms/uterine horn) from day 11 to day 15 post-oestrus (oestrus = day 0) could alter the binding capacities of endometrial receptors for oxytocin, progesterone and oestrogen in cyclic ewes when compared with control ewes receiving serum protein (SP) injections. Injections of oCSP on days 11-15 post-oestrus decreased concentrations of oestrogen receptors (P < 0.06), oestrogen receptor mRNA (P < 0.05) and progesterone receptors (P < 0.08) in endometrium on day 16 when compared with SP-infused control ewes, which were undergoing corpus luteum regression on days 14-16. Injection of oCSP also decreased the number (P < 0.10) and affinity (P < 0.06) of oxytocin receptors. Inositol phosphate formation induced in the endometrium on day 16 by 100 nM oxytocin in vitro was highly correlated with the concentration (r > or = 0.93, P < 0.001) and Kd (r = -0.91, P < 0.01) of oxytocin receptors in SP-infused ewes, but was not as highly correlated with concentration (r < or = 0.83, P < 0.06) and Kd (r < or = 0.40, P > 0.40) of oxytocin receptors in oCSP-infused ewes. This indicates that oCSP disrupted the relationship between oxytocin receptor binding and oxytocin-induced activation of its second messenger system. These results indicate that antiluteolytic type-I trophoblast interferon may prevent oxytocin-induced luteolytic pulsatile secretion of prostaglandin F2 alpha during maternal recognition of pregnancy in sheep, by reducing the synthesis and affinity of endometrial oxytocin receptors.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
- W2041938891 created "2016-06-24" @default.
- W2041938891 creator A5021286537 @default.
- W2041938891 creator A5037578514 @default.
- W2041938891 creator A5045794431 @default.
- W2041938891 creator A5047598837 @default.
- W2041938891 creator A5050774387 @default.
- W2041938891 creator A5069593347 @default.
- W2041938891 creator A5076716196 @default.
- W2041938891 date "1993-04-01" @default.
- W2041938891 modified "2023-09-25" @default.
- W2041938891 title "Changes in progesterone and oestrogen receptor mRNA and protein and oxytocin receptors in endometrium of ewes after intrauterine injection of ovine trophoblast interferon" @default.
- W2041938891 doi "https://doi.org/10.1677/jme.0.0100185" @default.
- W2041938891 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8387310" @default.
- W2041938891 hasPublicationYear "1993" @default.
- W2041938891 type Work @default.
- W2041938891 sameAs 2041938891 @default.
- W2041938891 citedByCount "31" @default.
- W2041938891 countsByYear W20419388912012 @default.
- W2041938891 countsByYear W20419388912017 @default.
- W2041938891 crossrefType "journal-article" @default.
- W2041938891 hasAuthorship W2041938891A5021286537 @default.
- W2041938891 hasAuthorship W2041938891A5037578514 @default.
- W2041938891 hasAuthorship W2041938891A5045794431 @default.
- W2041938891 hasAuthorship W2041938891A5047598837 @default.
- W2041938891 hasAuthorship W2041938891A5050774387 @default.
- W2041938891 hasAuthorship W2041938891A5069593347 @default.
- W2041938891 hasAuthorship W2041938891A5076716196 @default.
- W2041938891 hasConcept C126322002 @default.
- W2041938891 hasConcept C134018914 @default.
- W2041938891 hasConcept C170493617 @default.
- W2041938891 hasConcept C172680121 @default.
- W2041938891 hasConcept C181612422 @default.
- W2041938891 hasConcept C185592680 @default.
- W2041938891 hasConcept C1998276 @default.
- W2041938891 hasConcept C2776176026 @default.
- W2041938891 hasConcept C2776608385 @default.
- W2041938891 hasConcept C2776953305 @default.
- W2041938891 hasConcept C2777330693 @default.
- W2041938891 hasConcept C2777495146 @default.
- W2041938891 hasConcept C2778324911 @default.
- W2041938891 hasConcept C2779234561 @default.
- W2041938891 hasConcept C2779742232 @default.
- W2041938891 hasConcept C2780664492 @default.
- W2041938891 hasConcept C32253518 @default.
- W2041938891 hasConcept C54355233 @default.
- W2041938891 hasConcept C71924100 @default.
- W2041938891 hasConcept C86803240 @default.
- W2041938891 hasConceptScore W2041938891C126322002 @default.
- W2041938891 hasConceptScore W2041938891C134018914 @default.
- W2041938891 hasConceptScore W2041938891C170493617 @default.
- W2041938891 hasConceptScore W2041938891C172680121 @default.
- W2041938891 hasConceptScore W2041938891C181612422 @default.
- W2041938891 hasConceptScore W2041938891C185592680 @default.
- W2041938891 hasConceptScore W2041938891C1998276 @default.
- W2041938891 hasConceptScore W2041938891C2776176026 @default.
- W2041938891 hasConceptScore W2041938891C2776608385 @default.
- W2041938891 hasConceptScore W2041938891C2776953305 @default.
- W2041938891 hasConceptScore W2041938891C2777330693 @default.
- W2041938891 hasConceptScore W2041938891C2777495146 @default.
- W2041938891 hasConceptScore W2041938891C2778324911 @default.
- W2041938891 hasConceptScore W2041938891C2779234561 @default.
- W2041938891 hasConceptScore W2041938891C2779742232 @default.
- W2041938891 hasConceptScore W2041938891C2780664492 @default.
- W2041938891 hasConceptScore W2041938891C32253518 @default.
- W2041938891 hasConceptScore W2041938891C54355233 @default.
- W2041938891 hasConceptScore W2041938891C71924100 @default.
- W2041938891 hasConceptScore W2041938891C86803240 @default.
- W2041938891 hasIssue "2" @default.
- W2041938891 hasLocation W20419388911 @default.
- W2041938891 hasLocation W20419388912 @default.
- W2041938891 hasOpenAccess W2041938891 @default.
- W2041938891 hasPrimaryLocation W20419388911 @default.
- W2041938891 hasRelatedWork W187155899 @default.
- W2041938891 hasRelatedWork W1980995786 @default.
- W2041938891 hasRelatedWork W1994684987 @default.
- W2041938891 hasRelatedWork W2041938891 @default.
- W2041938891 hasRelatedWork W2062421381 @default.
- W2041938891 hasRelatedWork W2089365797 @default.
- W2041938891 hasRelatedWork W2101104217 @default.
- W2041938891 hasRelatedWork W2126160319 @default.
- W2041938891 hasRelatedWork W2416300785 @default.
- W2041938891 hasRelatedWork W2939595243 @default.
- W2041938891 hasVolume "10" @default.
- W2041938891 isParatext "false" @default.
- W2041938891 isRetracted "false" @default.
- W2041938891 magId "2041938891" @default.
- W2041938891 workType "article" @default.