Matches in SemOpenAlex for { <https://semopenalex.org/work/W2042117178> ?p ?o ?g. }
- W2042117178 abstract "Significance The continuous replenishment of differentiated cells, for example, those constituting the blood, involves proteins that control the generation and function of stem and progenitor cells. Although “master regulators” are implicated in these processes, many questions remain unanswered regarding how their synthesis and activities are regulated. We describe a mechanism that controls the production of the master regulator GATA binding protein-2 (GATA-2) in the context of blood stem and progenitor cells. Thousands of GATA-2 binding sites exist in the genome, and genetic analyses indicate that they differ greatly and unpredictably in functional importance. The parameters involved in endowing sites with functional activity are not established. We describe unique insights into ascertaining functionally important GATA-2 binding sites within chromosomes." @default.
- W2042117178 created "2016-06-24" @default.
- W2042117178 creator A5028884551 @default.
- W2042117178 creator A5032786824 @default.
- W2042117178 creator A5033357672 @default.
- W2042117178 creator A5050338164 @default.
- W2042117178 creator A5071365301 @default.
- W2042117178 creator A5083600842 @default.
- W2042117178 creator A5084525116 @default.
- W2042117178 creator A5088230370 @default.
- W2042117178 date "2014-03-10" @default.
- W2042117178 modified "2023-09-27" @default.
- W2042117178 title "Mechanism governing a stem cell-generating <i>cis</i> -regulatory element" @default.
- W2042117178 cites W115221593 @default.
- W2042117178 cites W1675282228 @default.
- W2042117178 cites W1822366055 @default.
- W2042117178 cites W1844168922 @default.
- W2042117178 cites W1966476720 @default.
- W2042117178 cites W1967558440 @default.
- W2042117178 cites W1970056549 @default.
- W2042117178 cites W1970831058 @default.
- W2042117178 cites W1971946672 @default.
- W2042117178 cites W1971958267 @default.
- W2042117178 cites W1974200066 @default.
- W2042117178 cites W1974203453 @default.
- W2042117178 cites W1982328581 @default.
- W2042117178 cites W1985739269 @default.
- W2042117178 cites W1987191562 @default.
- W2042117178 cites W1999047431 @default.
- W2042117178 cites W1999580244 @default.
- W2042117178 cites W2008051478 @default.
- W2042117178 cites W2008300544 @default.
- W2042117178 cites W2012170616 @default.
- W2042117178 cites W2015416439 @default.
- W2042117178 cites W2015584675 @default.
- W2042117178 cites W2018556284 @default.
- W2042117178 cites W2021516648 @default.
- W2042117178 cites W2021548599 @default.
- W2042117178 cites W2023229889 @default.
- W2042117178 cites W2024520070 @default.
- W2042117178 cites W2026688799 @default.
- W2042117178 cites W2027277319 @default.
- W2042117178 cites W2033904805 @default.
- W2042117178 cites W2034671907 @default.
- W2042117178 cites W2037688286 @default.
- W2042117178 cites W2042930277 @default.
- W2042117178 cites W2043753749 @default.
- W2042117178 cites W2044166133 @default.
- W2042117178 cites W2051740914 @default.
- W2042117178 cites W2061468315 @default.
- W2042117178 cites W2063380020 @default.
- W2042117178 cites W2063957967 @default.
- W2042117178 cites W2069314780 @default.
- W2042117178 cites W2079499097 @default.
- W2042117178 cites W2081755366 @default.
- W2042117178 cites W2086463181 @default.
- W2042117178 cites W2093050872 @default.
- W2042117178 cites W2093229652 @default.
- W2042117178 cites W2101590636 @default.
- W2042117178 cites W2102324931 @default.
- W2042117178 cites W2107746036 @default.
- W2042117178 cites W2109158516 @default.
- W2042117178 cites W2109719547 @default.
- W2042117178 cites W2110485236 @default.
- W2042117178 cites W2111868926 @default.
- W2042117178 cites W2114430445 @default.
- W2042117178 cites W2114717235 @default.
- W2042117178 cites W2116152510 @default.
- W2042117178 cites W2116584178 @default.
- W2042117178 cites W2119037385 @default.
- W2042117178 cites W2119375414 @default.
- W2042117178 cites W2119828465 @default.
- W2042117178 cites W2127559729 @default.
- W2042117178 cites W2129812210 @default.
- W2042117178 cites W2130699016 @default.
- W2042117178 cites W2135478764 @default.
- W2042117178 cites W2136182167 @default.
- W2042117178 cites W2138891173 @default.
- W2042117178 cites W2144500107 @default.
- W2042117178 cites W2150731845 @default.
- W2042117178 cites W2151754128 @default.
- W2042117178 cites W2162544653 @default.
- W2042117178 cites W2166309117 @default.
- W2042117178 cites W2259938310 @default.
- W2042117178 cites W3719606 @default.
- W2042117178 doi "https://doi.org/10.1073/pnas.1400065111" @default.
- W2042117178 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3970491" @default.
- W2042117178 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24616499" @default.
- W2042117178 hasPublicationYear "2014" @default.
- W2042117178 type Work @default.
- W2042117178 sameAs 2042117178 @default.
- W2042117178 citedByCount "38" @default.
- W2042117178 countsByYear W20421171782014 @default.
- W2042117178 countsByYear W20421171782015 @default.
- W2042117178 countsByYear W20421171782016 @default.
- W2042117178 countsByYear W20421171782017 @default.
- W2042117178 countsByYear W20421171782018 @default.
- W2042117178 countsByYear W20421171782019 @default.
- W2042117178 countsByYear W20421171782020 @default.
- W2042117178 countsByYear W20421171782021 @default.