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- W2042138823 abstract "Four populations of putative serotonergic cells could be detected in the chicken retina by histofluorescence and immunohistochemistry. Numerous (10,000/mm2) small (6 μm diameter) bipolar cells were located towards the middle of the inner nuclear layer, as were sparser (1000/mm2) larger (12 μm diameter) amacrine cells. Very sparse large (>30 μm diameter) and more numerous small (12 μm diameter) ganglion cells were also detected. Prominent fibre plexuses were detected in the inner plexiform layer, close to the inner nuclear and ganglion cell layers, and appeared to be formed by the processes of the bipolar cells, amacrine cells and at least the large ganglion cells. Exogenous serotonin (5-HT) was detected in the chicken retina. From the effects of neurotoxins on 5-HT levels and 5-HT-like immunoreactivity (5-HTLI), most of this appeared to be associated with the amacrine cells. 5-HTLI bipolar cells were selectively destroyed by intravitreal injections of 5–10 nmol of kainic acid, while 5-HTLIamacrine cells were destroyed by N-methyl-d,l-aspartic acid and 5,7-dihydroxytryptamine. The sensitivity of the bipolar cells to kainic acid indicates that they are OFF-cells." @default.
- W2042138823 created "2016-06-24" @default.
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- W2042138823 date "1988-01-01" @default.
- W2042138823 modified "2023-09-23" @default.
- W2042138823 title "Putative serotonergic bipolar and amacrine cells in the chicken retina" @default.
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- W2042138823 doi "https://doi.org/10.1016/0006-8993(88)91463-1" @default.
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