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- W2042183012 abstract "Summary: Hormonal and ultrastructural examinations of the testis were performed in an XX-male. Plasma levels of testosterone and prolactin were within the normal range, but FSH and LH were higher than the normal range. The response of testosterone to the administration of HCG is within the normal range. In the interstitium marked hyperplasia of Leydig cells was observed. The presence of paracrystalline inclusions and the absence of Reinke's crystals were representative changes in Leydig cells. Seminiferous tubules were filled with Sertoli cells and spermatogenesis was completely abolished. Intermediate filaments were abundant and annulate lamellae were absent in Sertoli cells. Zusammenfassung: Bei einem XX-Mann wurden Hormonanalysen und eine Ultrastruk-tur-Untersuchung des Hodengewebes durchgefuhrt. Während die Testosteron- und Prolak-tin-Werte normal ausfielen, lagen die Werte für FSH und LH im erhöhten Bereich. Nach HCG-Stimulierung ergab sich eine normale Testosteronreaktion. Histologisch lag eine deut-liche Leydig-Zell-Hyperplasie vor. Der Nachweis parakristalliner Einschlüsse und das Feh-len von Reinke-Kristallen waren repräsentative Veränderungen in den Leydig-Zellen. Die Tubuli seminiferi waren mit Sertolizellen angefüllt und die Spermatogenese fehlte voll-ständig. Intermediäre Filamente waren reichlich vorhanden und geringelte Lamellen fehl-ten in den Sertolizellen." @default.
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- W2042183012 date "2009-04-24" @default.
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- W2042183012 title "Ultrastructure of the Testis in an XX-Male with Normal Plasma Testosterone" @default.
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- W2042183012 doi "https://doi.org/10.1111/j.1439-0272.1986.tb01790.x" @default.
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