FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2042203667> ?p ?o ?g. }

• W2042203667 endingPage "666" @default.
• W2042203667 startingPage "655" @default.
• W2042203667 abstract "In rats anesthetized with urethane, a stimulating electrode was introduced to the locus coeruleus by observing the antidromic field response to single shock stimulation of the dorsal pathway of noradrenergic axons. Effects of locus coeruleus stimulation were studied on activities of relay neurons and intrinsic interneurons of the dorsal lateral geniculate nucleus and on those of neurons in the perigeniculate reticular nucleus. The intrinsic interneurons and the perigeniculate reticular neurons are believed to exert inhibition upon the relay neurons. The relay neurons were activated by repetitive stimulation of locus coeruleus; spontaneous discharges were increased in rate and the threshold of response to single shock stimulation of the optic nerve was lowered. The activation was rarely seen in rats pretreated with alpha-methyl-p-tyrosine. Iontophoretic application of phentolamine, an alpha-blocker, effectively antagonized the activation, whereas an iontophoretic beta-blocker and cholinergic blockers were virtually ineffective. The activation of the relay neurons was suggested to be due to a direct action of noradrenaline, released by locus coeruleus stimulation. Locus coeruleus stimulation inhibited the interneurons and activated the perigeniculate reticular neurons; spontaneous or light-evoked discharges were suppressed in the interneurons and tonic discharges were elicited in the perigeniculate reticular neurons. These effects of locus coeruleus stimulation were mimicked by noradrenaline applied iontophoretically. Activation of the perigeniculate reticular neurons was antagonized by an iontophoretic alpha-blocker but not by a beta-blocker. Two special features emerge from the present results: (1) the locus coeruleus exerts different effects upon the two neuronal constituents of the dorsal lateral geniculate nucleus, excitation of the relay neurons and inhibition of the intrinsic interneurons; (2) a suggestion previously advocated that locus-coeruleus-induced excitation of the lateral geniculate relay neurons would be due to inhibition of inhibitory neurons (disinhibition) does not hold true, at least with respect to the perigeniculate reticular neurons; the latter neurons have been proved to exert a powerful inhibition upon the geniculate relay neurons and they are excited by stimulation of the locus coeruleus." @default.
• W2042203667 created "2016-06-24" @default.
• W2042203667 creator A5012911527 @default.
• W2042203667 creator A5038368379 @default.
• W2042203667 creator A5039932033 @default.
• W2042203667 creator A5065698423 @default.
• W2042203667 date "1982-03-01" @default.
• W2042203667 modified "2023-09-27" @default.
• W2042203667 title "Effects of locus coeruleus stimulation on neuronal activities of dorsal lateral geniculate nucleus and perigeniculate reticular nucleus of the rat" @default.
• W2042203667 cites W1973691190 @default.
• W2042203667 cites W1989560145 @default.
• W2042203667 cites W1992597738 @default.
• W2042203667 cites W2004606702 @default.
• W2042203667 cites W2005161456 @default.
• W2042203667 cites W2010716926 @default.
• W2042203667 cites W2024861587 @default.
• W2042203667 cites W2036895913 @default.
• W2042203667 cites W2037550990 @default.
• W2042203667 cites W2041946981 @default.
• W2042203667 cites W2057621737 @default.
• W2042203667 cites W2149906893 @default.
• W2042203667 cites W2319009741 @default.
• W2042203667 cites W2333750611 @default.
• W2042203667 cites W2912505587 @default.
• W2042203667 doi "https://doi.org/10.1016/0306-4522(82)90071-9" @default.
• W2042203667 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6280101" @default.
• W2042203667 hasPublicationYear "1982" @default.
• W2042203667 type Work @default.
• W2042203667 sameAs 2042203667 @default.
• W2042203667 citedByCount "116" @default.
• W2042203667 countsByYear W20422036672013 @default.
• W2042203667 countsByYear W20422036672014 @default.
• W2042203667 countsByYear W20422036672015 @default.
• W2042203667 countsByYear W20422036672016 @default.
• W2042203667 countsByYear W20422036672017 @default.
• W2042203667 countsByYear W20422036672018 @default.
• W2042203667 countsByYear W20422036672019 @default.
• W2042203667 crossrefType "journal-article" @default.
• W2042203667 hasAuthorship W2042203667A5012911527 @default.
• W2042203667 hasAuthorship W2042203667A5038368379 @default.
• W2042203667 hasAuthorship W2042203667A5039932033 @default.
• W2042203667 hasAuthorship W2042203667A5065698423 @default.
• W2042203667 hasConcept C169760540 @default.
• W2042203667 hasConcept C185592680 @default.
• W2042203667 hasConcept C24998067 @default.
• W2042203667 hasConcept C2778468602 @default.
• W2042203667 hasConcept C2778655484 @default.
• W2042203667 hasConcept C2780253649 @default.
• W2042203667 hasConcept C2780723820 @default.
• W2042203667 hasConcept C86803240 @default.
• W2042203667 hasConceptScore W2042203667C169760540 @default.
• W2042203667 hasConceptScore W2042203667C185592680 @default.
• W2042203667 hasConceptScore W2042203667C24998067 @default.
• W2042203667 hasConceptScore W2042203667C2778468602 @default.
• W2042203667 hasConceptScore W2042203667C2778655484 @default.
• W2042203667 hasConceptScore W2042203667C2780253649 @default.
• W2042203667 hasConceptScore W2042203667C2780723820 @default.
• W2042203667 hasConceptScore W2042203667C86803240 @default.
• W2042203667 hasIssue "3" @default.
• W2042203667 hasLocation W20422036671 @default.
• W2042203667 hasLocation W20422036672 @default.
• W2042203667 hasOpenAccess W2042203667 @default.
• W2042203667 hasPrimaryLocation W20422036671 @default.
• W2042203667 hasRelatedWork W195219180 @default.
• W2042203667 hasRelatedWork W2017672299 @default.
• W2042203667 hasRelatedWork W2027136578 @default.
• W2042203667 hasRelatedWork W2028493865 @default.
• W2042203667 hasRelatedWork W2051573141 @default.
• W2042203667 hasRelatedWork W2085408819 @default.
• W2042203667 hasRelatedWork W2416197352 @default.
• W2042203667 hasRelatedWork W2754255220 @default.
• W2042203667 hasRelatedWork W2808726599 @default.
• W2042203667 hasRelatedWork W3013539571 @default.
• W2042203667 hasVolume "7" @default.
• W2042203667 isParatext "false" @default.
• W2042203667 isRetracted "false" @default.
• W2042203667 magId "2042203667" @default.
• W2042203667 workType "article" @default.