Matches in SemOpenAlex for { <https://semopenalex.org/work/W2042205488> ?p ?o ?g. }
- W2042205488 endingPage "2007" @default.
- W2042205488 startingPage "1997" @default.
- W2042205488 abstract "Vascular endothelial growth factor (VEGF) is produced in neoplastic cells in various myeloid neoplasms and may act as an autocrine growth-regulator. We have examined the expression of five VEGF receptors (VEGR1/Flt-1, VEGFR2/KDR, Flt-4, neuropilin-1 = NRP-1, NRP-2) in leukemic cells obtained from patients with acute myeloid leukemia (n = 28), chronic myeloid leukemia (n = 14), chronic eosinophilic leukemia (n = 3), chronic myelomonocytic leukemia (n = 9), or mast cell leukemia/systemic mastocytosis (n = 3) as well as in respective cell lines. Expression of VEGFR mRNA was analyzed by RT-PCR, and expression of VEGFR protein by immunocytochemistry. In most patients, leukemic cells expressed NRP-1 mRNA and NRP-2 mRNA independent of the type of disease. By contrast, transcripts for Flt-1, KDR, and Flt-4 were expressed variably without a clear correlation to the type of leukemia. Expression of VEGF receptors was also demonstrable at the protein level in all cases tested. In conclusion, neoplastic cells in myeloid leukemias frequently express VEGFR including NRP-1 and NRP-2." @default.
- W2042205488 created "2016-06-24" @default.
- W2042205488 creator A5006306448 @default.
- W2042205488 creator A5010063260 @default.
- W2042205488 creator A5018136553 @default.
- W2042205488 creator A5025735101 @default.
- W2042205488 creator A5034222353 @default.
- W2042205488 creator A5039634167 @default.
- W2042205488 creator A5047642347 @default.
- W2042205488 creator A5072949561 @default.
- W2042205488 creator A5084987088 @default.
- W2042205488 date "2007-01-01" @default.
- W2042205488 modified "2023-10-03" @default.
- W2042205488 title "Myeloid leukemias express a broad spectrum of VEGF receptors including neuropilin-1 (NRP-1) and NRP-2" @default.
- W2042205488 cites W109806565 @default.
- W2042205488 cites W135651168 @default.
- W2042205488 cites W153220058 @default.
- W2042205488 cites W1569016295 @default.
- W2042205488 cites W1600542667 @default.
- W2042205488 cites W16652925 @default.
- W2042205488 cites W1968870589 @default.
- W2042205488 cites W1972434392 @default.
- W2042205488 cites W1985325453 @default.
- W2042205488 cites W1988186967 @default.
- W2042205488 cites W1988689365 @default.
- W2042205488 cites W1989445047 @default.
- W2042205488 cites W1990607283 @default.
- W2042205488 cites W1993327121 @default.
- W2042205488 cites W1993459405 @default.
- W2042205488 cites W1994953133 @default.
- W2042205488 cites W2000292756 @default.
- W2042205488 cites W2010114646 @default.
- W2042205488 cites W2015867957 @default.
- W2042205488 cites W2016656445 @default.
- W2042205488 cites W2024510824 @default.
- W2042205488 cites W2030025004 @default.
- W2042205488 cites W2038448524 @default.
- W2042205488 cites W2043488365 @default.
- W2042205488 cites W2068701609 @default.
- W2042205488 cites W2076426515 @default.
- W2042205488 cites W2082869698 @default.
- W2042205488 cites W2083364212 @default.
- W2042205488 cites W2084944550 @default.
- W2042205488 cites W2088040320 @default.
- W2042205488 cites W2090658143 @default.
- W2042205488 cites W2106019508 @default.
- W2042205488 cites W2111874221 @default.
- W2042205488 cites W2140024288 @default.
- W2042205488 cites W2142047303 @default.
- W2042205488 cites W2145693683 @default.
- W2042205488 cites W3196347549 @default.
- W2042205488 doi "https://doi.org/10.1080/10428190701534424" @default.
- W2042205488 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17917967" @default.
- W2042205488 hasPublicationYear "2007" @default.
- W2042205488 type Work @default.
- W2042205488 sameAs 2042205488 @default.
- W2042205488 citedByCount "34" @default.
- W2042205488 countsByYear W20422054882012 @default.
- W2042205488 countsByYear W20422054882013 @default.
- W2042205488 countsByYear W20422054882014 @default.
- W2042205488 countsByYear W20422054882015 @default.
- W2042205488 countsByYear W20422054882017 @default.
- W2042205488 countsByYear W20422054882018 @default.
- W2042205488 countsByYear W20422054882019 @default.
- W2042205488 countsByYear W20422054882020 @default.
- W2042205488 countsByYear W20422054882021 @default.
- W2042205488 countsByYear W20422054882022 @default.
- W2042205488 countsByYear W20422054882023 @default.
- W2042205488 crossrefType "journal-article" @default.
- W2042205488 hasAuthorship W2042205488A5006306448 @default.
- W2042205488 hasAuthorship W2042205488A5010063260 @default.
- W2042205488 hasAuthorship W2042205488A5018136553 @default.
- W2042205488 hasAuthorship W2042205488A5025735101 @default.
- W2042205488 hasAuthorship W2042205488A5034222353 @default.
- W2042205488 hasAuthorship W2042205488A5039634167 @default.
- W2042205488 hasAuthorship W2042205488A5047642347 @default.
- W2042205488 hasAuthorship W2042205488A5072949561 @default.
- W2042205488 hasAuthorship W2042205488A5084987088 @default.
- W2042205488 hasConcept C126322002 @default.
- W2042205488 hasConcept C128240485 @default.
- W2042205488 hasConcept C167734588 @default.
- W2042205488 hasConcept C170493617 @default.
- W2042205488 hasConcept C203014093 @default.
- W2042205488 hasConcept C2777025900 @default.
- W2042205488 hasConcept C2778461978 @default.
- W2042205488 hasConcept C2778729363 @default.
- W2042205488 hasConcept C2779282312 @default.
- W2042205488 hasConcept C34425596 @default.
- W2042205488 hasConcept C502942594 @default.
- W2042205488 hasConcept C71924100 @default.
- W2042205488 hasConcept C86803240 @default.
- W2042205488 hasConceptScore W2042205488C126322002 @default.
- W2042205488 hasConceptScore W2042205488C128240485 @default.
- W2042205488 hasConceptScore W2042205488C167734588 @default.
- W2042205488 hasConceptScore W2042205488C170493617 @default.
- W2042205488 hasConceptScore W2042205488C203014093 @default.
- W2042205488 hasConceptScore W2042205488C2777025900 @default.
- W2042205488 hasConceptScore W2042205488C2778461978 @default.