Matches in SemOpenAlex for { <https://semopenalex.org/work/W2042237322> ?p ?o ?g. }
- W2042237322 endingPage "150" @default.
- W2042237322 startingPage "143" @default.
- W2042237322 abstract "Progesterone and progestin receptors (PRs) are known to play a role in the development of brain physiology and behavior in many different species. The distribution and regulation of PRs within the developing brain suggest that they likely contribute to the organization of the brain and behavior in a sex-specific manner. We examined the role of PR signaling during development on the organization of adult sexual behavior and androgen receptor (AR) expression in the brain. We administered the PR antagonist, RU-486, subcutaneously to male and female rats on postnatal days 1-7 (0=day of birth) and examined adult sexual behavior and AR-immunoreactivity (AR-ir) in the adult brain. A typical sex difference in lordosis quotient (LQ) was observed and neonatal RU-486 treatment did not alter this behavior. In contrast, neonatal RU-486 treatment increased adult male sexual behavior and AR-ir in several brain areas in males. These data indicate that a transient disruption in PR signaling during development can have lasting consequences on the male brain and may increase male sexual behavior in part by increasing AR expression, and therefore androgen sensitivity, in adulthood." @default.
- W2042237322 created "2016-06-24" @default.
- W2042237322 creator A5009815719 @default.
- W2042237322 creator A5014200487 @default.
- W2042237322 creator A5091721055 @default.
- W2042237322 date "2014-01-01" @default.
- W2042237322 modified "2023-10-16" @default.
- W2042237322 title "Neonatal RU-486 (mifepristone) exposure increases androgen receptor immunoreactivity and sexual behavior in male rats" @default.
- W2042237322 cites W1484666375 @default.
- W2042237322 cites W1975442007 @default.
- W2042237322 cites W1978110594 @default.
- W2042237322 cites W1982338117 @default.
- W2042237322 cites W1982488750 @default.
- W2042237322 cites W1987953960 @default.
- W2042237322 cites W1989173141 @default.
- W2042237322 cites W1991847593 @default.
- W2042237322 cites W1996011857 @default.
- W2042237322 cites W1999186716 @default.
- W2042237322 cites W2002653885 @default.
- W2042237322 cites W2003860461 @default.
- W2042237322 cites W2007651234 @default.
- W2042237322 cites W2010960071 @default.
- W2042237322 cites W2016704563 @default.
- W2042237322 cites W2024416905 @default.
- W2042237322 cites W2025956305 @default.
- W2042237322 cites W2028117758 @default.
- W2042237322 cites W2031156296 @default.
- W2042237322 cites W2033259793 @default.
- W2042237322 cites W2034660732 @default.
- W2042237322 cites W2039258787 @default.
- W2042237322 cites W2052435478 @default.
- W2042237322 cites W2053761518 @default.
- W2042237322 cites W2056734403 @default.
- W2042237322 cites W2080255498 @default.
- W2042237322 cites W2083242486 @default.
- W2042237322 cites W2084046924 @default.
- W2042237322 cites W2084125442 @default.
- W2042237322 cites W2084498799 @default.
- W2042237322 cites W2085369703 @default.
- W2042237322 cites W2103948764 @default.
- W2042237322 cites W2122812350 @default.
- W2042237322 cites W2122860707 @default.
- W2042237322 cites W2134412827 @default.
- W2042237322 cites W2144570917 @default.
- W2042237322 cites W2155107774 @default.
- W2042237322 cites W2161218552 @default.
- W2042237322 doi "https://doi.org/10.1016/j.brainres.2013.11.012" @default.
- W2042237322 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24239933" @default.
- W2042237322 hasPublicationYear "2014" @default.
- W2042237322 type Work @default.
- W2042237322 sameAs 2042237322 @default.
- W2042237322 citedByCount "11" @default.
- W2042237322 countsByYear W20422373222015 @default.
- W2042237322 countsByYear W20422373222016 @default.
- W2042237322 countsByYear W20422373222017 @default.
- W2042237322 countsByYear W20422373222019 @default.
- W2042237322 countsByYear W20422373222021 @default.
- W2042237322 countsByYear W20422373222023 @default.
- W2042237322 crossrefType "journal-article" @default.
- W2042237322 hasAuthorship W2042237322A5009815719 @default.
- W2042237322 hasAuthorship W2042237322A5014200487 @default.
- W2042237322 hasAuthorship W2042237322A5091721055 @default.
- W2042237322 hasConcept C104317684 @default.
- W2042237322 hasConcept C121608353 @default.
- W2042237322 hasConcept C126322002 @default.
- W2042237322 hasConcept C134018914 @default.
- W2042237322 hasConcept C138496976 @default.
- W2042237322 hasConcept C15744967 @default.
- W2042237322 hasConcept C170493617 @default.
- W2042237322 hasConcept C2777911890 @default.
- W2042237322 hasConcept C2778826759 @default.
- W2042237322 hasConcept C2779234561 @default.
- W2042237322 hasConcept C2779279991 @default.
- W2042237322 hasConcept C2780192828 @default.
- W2042237322 hasConcept C2993290233 @default.
- W2042237322 hasConcept C54355233 @default.
- W2042237322 hasConcept C55493867 @default.
- W2042237322 hasConcept C61367390 @default.
- W2042237322 hasConcept C63405245 @default.
- W2042237322 hasConcept C71315377 @default.
- W2042237322 hasConcept C71924100 @default.
- W2042237322 hasConcept C86803240 @default.
- W2042237322 hasConceptScore W2042237322C104317684 @default.
- W2042237322 hasConceptScore W2042237322C121608353 @default.
- W2042237322 hasConceptScore W2042237322C126322002 @default.
- W2042237322 hasConceptScore W2042237322C134018914 @default.
- W2042237322 hasConceptScore W2042237322C138496976 @default.
- W2042237322 hasConceptScore W2042237322C15744967 @default.
- W2042237322 hasConceptScore W2042237322C170493617 @default.
- W2042237322 hasConceptScore W2042237322C2777911890 @default.
- W2042237322 hasConceptScore W2042237322C2778826759 @default.
- W2042237322 hasConceptScore W2042237322C2779234561 @default.
- W2042237322 hasConceptScore W2042237322C2779279991 @default.
- W2042237322 hasConceptScore W2042237322C2780192828 @default.
- W2042237322 hasConceptScore W2042237322C2993290233 @default.
- W2042237322 hasConceptScore W2042237322C54355233 @default.
- W2042237322 hasConceptScore W2042237322C55493867 @default.
- W2042237322 hasConceptScore W2042237322C61367390 @default.