Matches in SemOpenAlex for { <https://semopenalex.org/work/W2042246477> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2042246477 abstract "A simple, rapid, selective, sensitive, linear, precise and accurate stability indicating RP-HPLC method was developed and validated for the simultaneous estimation of Atenolol and Nifedipine in pharmaceutical dosage form. Separation was attained on a STD Kromasil C18 (150 x 4.6 mm, 5 μ particle size) column at 30°C using a mobile phase consisting of phosphate buffer (pH 5.0) and acetonitrile in the ratio of 45: 55% v/v, at a flow rate of 1.0 ml/min. The UV detection wavelength was 232 nm and 10 μl of sample was injected. The linearity was found to be 15–90 μg/ml for Atenolol and 6–36 μg/ml for Nifedipine with a correlation coefficient of 0.9993 and 0.9994, respectively. Retention times were found to be 2.474 min and 4.553 min for Atenolol and Nifedipine, respectively. The overall mean % recoveries were found to be 99.69% for Atenolol and 99.68% for Nifedipine. The method was validated as per the ICH guidelines for sensitivity, linearity, accuracy and precision. The % RSD for precision, robustness and ruggedness of the proposed method was found to be less than 2%. Further forced degradation studies were conducted for indicating the stability of the method developed. Hence the developed method can be successfully employed for routine quality control analysis of Atenolol and Nifedipine in pharmaceutical dosage forms." @default.
- W2042246477 created "2016-06-24" @default.
- W2042246477 creator A5023755087 @default.
- W2042246477 creator A5034368408 @default.
- W2042246477 creator A5069991075 @default.
- W2042246477 creator A5081865600 @default.
- W2042246477 date "2015-01-01" @default.
- W2042246477 modified "2023-09-27" @default.
- W2042246477 title "Development and validation of stability indicating RP-HPLC method for simultaneous estimation of Atenolol and Nifedipine in bulk and pharmaceutical dosage form" @default.
- W2042246477 doi "https://doi.org/10.5958/0974-4150.2015.00017.6" @default.
- W2042246477 hasPublicationYear "2015" @default.
- W2042246477 type Work @default.
- W2042246477 sameAs 2042246477 @default.
- W2042246477 citedByCount "1" @default.
- W2042246477 countsByYear W20422464772022 @default.
- W2042246477 crossrefType "journal-article" @default.
- W2042246477 hasAuthorship W2042246477A5023755087 @default.
- W2042246477 hasAuthorship W2042246477A5034368408 @default.
- W2042246477 hasAuthorship W2042246477A5069991075 @default.
- W2042246477 hasAuthorship W2042246477A5081865600 @default.
- W2042246477 hasConcept C105795698 @default.
- W2042246477 hasConcept C126322002 @default.
- W2042246477 hasConcept C178790620 @default.
- W2042246477 hasConcept C179998833 @default.
- W2042246477 hasConcept C185592680 @default.
- W2042246477 hasConcept C2776525901 @default.
- W2042246477 hasConcept C2777463227 @default.
- W2042246477 hasConcept C2779066535 @default.
- W2042246477 hasConcept C2780092901 @default.
- W2042246477 hasConcept C3020018676 @default.
- W2042246477 hasConcept C33923547 @default.
- W2042246477 hasConcept C43617362 @default.
- W2042246477 hasConcept C519063684 @default.
- W2042246477 hasConcept C71924100 @default.
- W2042246477 hasConcept C77281830 @default.
- W2042246477 hasConcept C84393581 @default.
- W2042246477 hasConcept C96616956 @default.
- W2042246477 hasConceptScore W2042246477C105795698 @default.
- W2042246477 hasConceptScore W2042246477C126322002 @default.
- W2042246477 hasConceptScore W2042246477C178790620 @default.
- W2042246477 hasConceptScore W2042246477C179998833 @default.
- W2042246477 hasConceptScore W2042246477C185592680 @default.
- W2042246477 hasConceptScore W2042246477C2776525901 @default.
- W2042246477 hasConceptScore W2042246477C2777463227 @default.
- W2042246477 hasConceptScore W2042246477C2779066535 @default.
- W2042246477 hasConceptScore W2042246477C2780092901 @default.
- W2042246477 hasConceptScore W2042246477C3020018676 @default.
- W2042246477 hasConceptScore W2042246477C33923547 @default.
- W2042246477 hasConceptScore W2042246477C43617362 @default.
- W2042246477 hasConceptScore W2042246477C519063684 @default.
- W2042246477 hasConceptScore W2042246477C71924100 @default.
- W2042246477 hasConceptScore W2042246477C77281830 @default.
- W2042246477 hasConceptScore W2042246477C84393581 @default.
- W2042246477 hasConceptScore W2042246477C96616956 @default.
- W2042246477 hasLocation W20422464771 @default.
- W2042246477 hasOpenAccess W2042246477 @default.
- W2042246477 hasPrimaryLocation W20422464771 @default.
- W2042246477 hasRelatedWork W1500114988 @default.
- W2042246477 hasRelatedWork W2119407742 @default.
- W2042246477 hasRelatedWork W2130013232 @default.
- W2042246477 hasRelatedWork W2223189218 @default.
- W2042246477 hasRelatedWork W2228409440 @default.
- W2042246477 hasRelatedWork W2253069004 @default.
- W2042246477 hasRelatedWork W2256050729 @default.
- W2042246477 hasRelatedWork W2264763776 @default.
- W2042246477 hasRelatedWork W2265655132 @default.
- W2042246477 hasRelatedWork W2270793337 @default.
- W2042246477 hasRelatedWork W2272344929 @default.
- W2042246477 hasRelatedWork W2278498629 @default.
- W2042246477 hasRelatedWork W2338116339 @default.
- W2042246477 hasRelatedWork W2790562065 @default.
- W2042246477 hasRelatedWork W2807750066 @default.
- W2042246477 hasRelatedWork W2883961998 @default.
- W2042246477 hasRelatedWork W2995626162 @default.
- W2042246477 hasRelatedWork W3005537468 @default.
- W2042246477 hasRelatedWork W3008456156 @default.
- W2042246477 hasRelatedWork W3021034151 @default.
- W2042246477 isParatext "false" @default.
- W2042246477 isRetracted "false" @default.
- W2042246477 magId "2042246477" @default.
- W2042246477 workType "article" @default.