Matches in SemOpenAlex for { <https://semopenalex.org/work/W2042252507> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2042252507 endingPage "344" @default.
- W2042252507 startingPage "339" @default.
- W2042252507 abstract "In Brief Purpose: The most difficult and unpredictable step of macular translocation surgery is creating the retinal detachment. The authors evaluated the efficacy of 2,4-dinitrophenol (2,4-DNP) to promote retinal detachment in the rabbit. Methods: A vitrectomy was performed in each eye of a Dutch-belted rabbit. One eye was injected with 0.1 cc of a 5 mmol/L 2,4-DNP, the other eye with 0.1 cc of BSS+. After 30 minutes, the minimum aspiration pressure required to visibly elevate the retina was recorded. Four nonvitrectomized eyes received an intravitreal injection of either 0.1 cc of BSS+ or 5 mmol/L 2,4-DNP, and were enucleated and fixated for histopathologic examination. Results: In the 12 masked eyes, the mean aspiration pressure decreased from 217 ± 20 mmHg in the six BSS+ eyes to 117 ± 20 mmHg in the six 2,4-DNP treated eyes (P = 0.0022). A retinal detachment was present in three of six masked and two of two unmasked 2,4-DNP treated eyes and none of eight BSS+ treated eyes. There was no short-term toxicity to the retina at the light microscope level. Conclusion: Intravitreal injection of 2,4-DNP reduced the retinal adhesive force by over 50% when compared to the BSS+ treated control eyes, without any short-term retinal toxicity. 2,4-dinitrophenol (2,4-DNP) is an effective promoter of retinal detachment in the rabbit model. A single intravitreal injection of 0.1 cc of 5 mmol/L 2,4-DNP (92 g) reduced the retinal adhesive force by more than 50% when compared to the BSS treated control eyes at 30 minutes." @default.
- W2042252507 created "2016-06-24" @default.
- W2042252507 creator A5008489709 @default.
- W2042252507 creator A5029514850 @default.
- W2042252507 creator A5033919092 @default.
- W2042252507 creator A5051010808 @default.
- W2042252507 creator A5060847143 @default.
- W2042252507 creator A5076515408 @default.
- W2042252507 date "2005-04-01" @default.
- W2042252507 modified "2023-10-14" @default.
- W2042252507 title "2,4–DINITROPHENOL PHARMACOLOGICALLY PROMOTES RETINAL DETACHMENT IN RABBITS" @default.
- W2042252507 cites W2018119682 @default.
- W2042252507 cites W2049991231 @default.
- W2042252507 cites W2052946966 @default.
- W2042252507 cites W2071589120 @default.
- W2042252507 cites W2093340598 @default.
- W2042252507 cites W2094135392 @default.
- W2042252507 cites W2162153328 @default.
- W2042252507 cites W2317321136 @default.
- W2042252507 doi "https://doi.org/10.1097/00006982-200504000-00014" @default.
- W2042252507 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15805912" @default.
- W2042252507 hasPublicationYear "2005" @default.
- W2042252507 type Work @default.
- W2042252507 sameAs 2042252507 @default.
- W2042252507 citedByCount "1" @default.
- W2042252507 countsByYear W20422525072014 @default.
- W2042252507 crossrefType "journal-article" @default.
- W2042252507 hasAuthorship W2042252507A5008489709 @default.
- W2042252507 hasAuthorship W2042252507A5029514850 @default.
- W2042252507 hasAuthorship W2042252507A5033919092 @default.
- W2042252507 hasAuthorship W2042252507A5051010808 @default.
- W2042252507 hasAuthorship W2042252507A5060847143 @default.
- W2042252507 hasAuthorship W2042252507A5076515408 @default.
- W2042252507 hasConcept C118487528 @default.
- W2042252507 hasConcept C169760540 @default.
- W2042252507 hasConcept C185592680 @default.
- W2042252507 hasConcept C2777093970 @default.
- W2042252507 hasConcept C2778257484 @default.
- W2042252507 hasConcept C2780130669 @default.
- W2042252507 hasConcept C2780428090 @default.
- W2042252507 hasConcept C2780827179 @default.
- W2042252507 hasConcept C2781242345 @default.
- W2042252507 hasConcept C55493867 @default.
- W2042252507 hasConcept C71924100 @default.
- W2042252507 hasConcept C86803240 @default.
- W2042252507 hasConceptScore W2042252507C118487528 @default.
- W2042252507 hasConceptScore W2042252507C169760540 @default.
- W2042252507 hasConceptScore W2042252507C185592680 @default.
- W2042252507 hasConceptScore W2042252507C2777093970 @default.
- W2042252507 hasConceptScore W2042252507C2778257484 @default.
- W2042252507 hasConceptScore W2042252507C2780130669 @default.
- W2042252507 hasConceptScore W2042252507C2780428090 @default.
- W2042252507 hasConceptScore W2042252507C2780827179 @default.
- W2042252507 hasConceptScore W2042252507C2781242345 @default.
- W2042252507 hasConceptScore W2042252507C55493867 @default.
- W2042252507 hasConceptScore W2042252507C71924100 @default.
- W2042252507 hasConceptScore W2042252507C86803240 @default.
- W2042252507 hasIssue "3" @default.
- W2042252507 hasLocation W20422525071 @default.
- W2042252507 hasLocation W20422525072 @default.
- W2042252507 hasOpenAccess W2042252507 @default.
- W2042252507 hasPrimaryLocation W20422525071 @default.
- W2042252507 hasRelatedWork W1980076856 @default.
- W2042252507 hasRelatedWork W2005639104 @default.
- W2042252507 hasRelatedWork W2092660047 @default.
- W2042252507 hasRelatedWork W2315642745 @default.
- W2042252507 hasRelatedWork W2392302292 @default.
- W2042252507 hasRelatedWork W2643064894 @default.
- W2042252507 hasRelatedWork W3030283649 @default.
- W2042252507 hasRelatedWork W3030525026 @default.
- W2042252507 hasRelatedWork W3209351225 @default.
- W2042252507 hasRelatedWork W4384944007 @default.
- W2042252507 hasVolume "25" @default.
- W2042252507 isParatext "false" @default.
- W2042252507 isRetracted "false" @default.
- W2042252507 magId "2042252507" @default.
- W2042252507 workType "article" @default.