Matches in SemOpenAlex for { <https://semopenalex.org/work/W2042287679> ?p ?o ?g. }
- W2042287679 endingPage "1163" @default.
- W2042287679 startingPage "1154" @default.
- W2042287679 abstract "Posttraumatic stress disorder (PTSD) is characterized by the presence of anatomo-functional hippocampal alterations. To date, the ability to orient within the environment, which relies on hippocampal integrity, has never been investigated in PTSD. We hypothesized that the ability to form a cognitive map of the environment would be impaired in PTSD. Moreover, spatial memory consolidation benefits from postlearning sleep. Because PTSD individuals often complain about sleep disturbances, we hypothesized that any sleep effect on memory performance would be hampered in these subjects. Twenty-two subjects, all survivors of the L'Aquila 2009 earthquake, were divided into a PTSD and a control group, based on clinical evaluation. After an acquisition phase, they were tested twice (“test” and “retest”) on a virtual navigation task. In addition, participants were administered the Digit Span and Task Switching. Subjective sleep quality and sleep disturbances were also assessed. The two testing sessions were on consecutive mornings, interspersed with a night of sleep. During the acquisition phase, the PTSD group took more than twice as long to form a cognitive map of the environment compared to the control group. However, once this phase was successfully completed, the two groups did not differ at test, but they tendentially differed at postsleep retest. Additional analyses comparing performances between groups on test–retest difference scores confirm that sleep-dependent consolidation may be differentially affected in the two groups. Our findings are strictly confined to the navigation performance, excluding a generalized cognitive deficit. PTSD also reported more subjective sleep disturbances and shorter sleep time than controls, which were correlated to worse performance at retest. The specific deficit in the formation of a cognitive map reported in PTSD may be related to hippocampal dysfunctions as well as to the sleep disturbances experienced by these patients. The possible deficiency of sleep-dependent spatial performance improvement should however be confirmed by further studies comprising a wake control group. © 2011 Wiley Periodicals, Inc." @default.
- W2042287679 created "2016-06-24" @default.
- W2042287679 creator A5009487497 @default.
- W2042287679 creator A5018843327 @default.
- W2042287679 creator A5022042138 @default.
- W2042287679 creator A5042951463 @default.
- W2042287679 creator A5087285352 @default.
- W2042287679 date "2011-07-07" @default.
- W2042287679 modified "2023-09-24" @default.
- W2042287679 title "A specific deficit in spatial memory acquisition in post-traumatic stress disorder and the role of sleep in its consolidation" @default.
- W2042287679 cites W1499701307 @default.
- W2042287679 cites W170792860 @default.
- W2042287679 cites W1972203577 @default.
- W2042287679 cites W1978905432 @default.
- W2042287679 cites W1994547251 @default.
- W2042287679 cites W1996935070 @default.
- W2042287679 cites W1999482294 @default.
- W2042287679 cites W2015599670 @default.
- W2042287679 cites W2017588681 @default.
- W2042287679 cites W2027845679 @default.
- W2042287679 cites W2034225478 @default.
- W2042287679 cites W2044146277 @default.
- W2042287679 cites W2045217506 @default.
- W2042287679 cites W2051390237 @default.
- W2042287679 cites W2052515926 @default.
- W2042287679 cites W2064212981 @default.
- W2042287679 cites W2068152903 @default.
- W2042287679 cites W2068659456 @default.
- W2042287679 cites W2071290167 @default.
- W2042287679 cites W2079488381 @default.
- W2042287679 cites W2085894775 @default.
- W2042287679 cites W2088631918 @default.
- W2042287679 cites W2092481091 @default.
- W2042287679 cites W2108619726 @default.
- W2042287679 cites W2114890135 @default.
- W2042287679 cites W2118439943 @default.
- W2042287679 cites W2122833757 @default.
- W2042287679 cites W2124403912 @default.
- W2042287679 cites W2127369497 @default.
- W2042287679 cites W2128552517 @default.
- W2042287679 cites W2129440177 @default.
- W2042287679 cites W2132720746 @default.
- W2042287679 cites W2139502395 @default.
- W2042287679 cites W2150002746 @default.
- W2042287679 cites W2151487996 @default.
- W2042287679 cites W2154099072 @default.
- W2042287679 cites W2158352058 @default.
- W2042287679 cites W2158446241 @default.
- W2042287679 cites W2168101731 @default.
- W2042287679 cites W2171103528 @default.
- W2042287679 cites W2219191873 @default.
- W2042287679 cites W4230642005 @default.
- W2042287679 cites W4238879677 @default.
- W2042287679 cites W4245942401 @default.
- W2042287679 cites W4249129794 @default.
- W2042287679 doi "https://doi.org/10.1002/hipo.20961" @default.
- W2042287679 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21739522" @default.
- W2042287679 hasPublicationYear "2011" @default.
- W2042287679 type Work @default.
- W2042287679 sameAs 2042287679 @default.
- W2042287679 citedByCount "36" @default.
- W2042287679 countsByYear W20422876792012 @default.
- W2042287679 countsByYear W20422876792013 @default.
- W2042287679 countsByYear W20422876792014 @default.
- W2042287679 countsByYear W20422876792015 @default.
- W2042287679 countsByYear W20422876792016 @default.
- W2042287679 countsByYear W20422876792017 @default.
- W2042287679 countsByYear W20422876792018 @default.
- W2042287679 countsByYear W20422876792019 @default.
- W2042287679 countsByYear W20422876792020 @default.
- W2042287679 countsByYear W20422876792021 @default.
- W2042287679 countsByYear W20422876792022 @default.
- W2042287679 crossrefType "journal-article" @default.
- W2042287679 hasAuthorship W2042287679A5009487497 @default.
- W2042287679 hasAuthorship W2042287679A5018843327 @default.
- W2042287679 hasAuthorship W2042287679A5022042138 @default.
- W2042287679 hasAuthorship W2042287679A5042951463 @default.
- W2042287679 hasAuthorship W2042287679A5087285352 @default.
- W2042287679 hasConcept C111919701 @default.
- W2042287679 hasConcept C118552586 @default.
- W2042287679 hasConcept C15744967 @default.
- W2042287679 hasConcept C169760540 @default.
- W2042287679 hasConcept C169900460 @default.
- W2042287679 hasConcept C2775841894 @default.
- W2042287679 hasConcept C2781161787 @default.
- W2042287679 hasConcept C2991847609 @default.
- W2042287679 hasConcept C41008148 @default.
- W2042287679 hasConcept C48455012 @default.
- W2042287679 hasConcept C548259974 @default.
- W2042287679 hasConcept C70410870 @default.
- W2042287679 hasConcept C71924100 @default.
- W2042287679 hasConceptScore W2042287679C111919701 @default.
- W2042287679 hasConceptScore W2042287679C118552586 @default.
- W2042287679 hasConceptScore W2042287679C15744967 @default.
- W2042287679 hasConceptScore W2042287679C169760540 @default.
- W2042287679 hasConceptScore W2042287679C169900460 @default.
- W2042287679 hasConceptScore W2042287679C2775841894 @default.
- W2042287679 hasConceptScore W2042287679C2781161787 @default.