FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2042316831> ?p ?o ?g. }

• W2042316831 endingPage "53" @default.
• W2042316831 startingPage "49" @default.
• W2042316831 abstract "Intraluminal fat inhibits gastric secretion through as yet undetermined mechanisms which involve release of one or more hormonal enterogastrones. As intraluminal fat releases Peptide YY (PYY) in amounts sufficient to inhibit meal-stimulated acid secretion, this ileo-colonic peptide exhibits the characteristics required of an enterogastrone. The present study seeks to determine the mechanism by which PYY inhibits acid secretion by examining the effects of PYY on gastric acid stimulated by pentagastrin, histamine, and bethanechol. In addition, effects of PYY on the acid response to sham feeding and distention of a denervated gastric pouch were examined. A dose of PYY (400 pmol X kg-1 X h-1) was employed that reproduced blood levels observed after intestinal perfusion with oleic acid and inhibited the acid secretory response to an intragastric meal by 35 +/- 6%. This same dose of PYY maximally inhibited histamine- and pentagastrin-stimulated acid secretion by 28 +/- 7% (P less than 0.05), and 17 +/- 4% (P less than 0.05), respectively. Although PYY had no effect on bethanechol-stimulated secretion it markedly inhibited the secretory response to sham feeding, maximally reducing secretion by 90 +/- 4% (P less than 0.01). We speculate that PYY acts by inhibiting acetylcholine release from vagal nerve fibers rather than by inhibiting acetylcholine's action on the parietal cell. The demonstration that PYY virtually abolishes cephalic phase acid secretion while having little if any effect on the response to exogenous secretogogues gives PYY unique characteristics among the known hormonal inhibitors of gastric secretion." @default.
• W2042316831 created "2016-06-24" @default.
• W2042316831 creator A5020460397 @default.
• W2042316831 creator A5050485042 @default.
• W2042316831 creator A5051554049 @default.
• W2042316831 date "1986-01-01" @default.
• W2042316831 modified "2023-10-14" @default.
• W2042316831 title "Enterogastrone-like effect of peptide YY is vagally mediated in the dog." @default.
• W2042316831 cites W1574168824 @default.
• W2042316831 cites W1650823630 @default.
• W2042316831 cites W1971699667 @default.
• W2042316831 cites W1979456394 @default.
• W2042316831 cites W1982580636 @default.
• W2042316831 cites W1999598420 @default.
• W2042316831 cites W202436233 @default.
• W2042316831 cites W2041092623 @default.
• W2042316831 cites W2052519819 @default.
• W2042316831 cites W2056620189 @default.
• W2042316831 cites W2064474849 @default.
• W2042316831 cites W2079042881 @default.
• W2042316831 cites W2083686894 @default.
• W2042316831 cites W2117210104 @default.
• W2042316831 cites W2147701049 @default.
• W2042316831 cites W2428951691 @default.
• W2042316831 doi "https://doi.org/10.1172/jci112300" @default.
• W2042316831 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/423307" @default.
• W2042316831 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2868024" @default.
• W2042316831 hasPublicationYear "1986" @default.
• W2042316831 type Work @default.
• W2042316831 sameAs 2042316831 @default.
• W2042316831 citedByCount "92" @default.
• W2042316831 countsByYear W20423168312012 @default.
• W2042316831 countsByYear W20423168312015 @default.
• W2042316831 countsByYear W20423168312016 @default.
• W2042316831 countsByYear W20423168312019 @default.
• W2042316831 countsByYear W20423168312022 @default.
• W2042316831 crossrefType "journal-article" @default.
• W2042316831 hasAuthorship W2042316831A5020460397 @default.
• W2042316831 hasAuthorship W2042316831A5050485042 @default.
• W2042316831 hasAuthorship W2042316831A5051554049 @default.
• W2042316831 hasBestOaLocation W20423168311 @default.
• W2042316831 hasConcept C1122143 @default.
• W2042316831 hasConcept C118303440 @default.
• W2042316831 hasConcept C126322002 @default.
• W2042316831 hasConcept C134018914 @default.
• W2042316831 hasConcept C170493617 @default.
• W2042316831 hasConcept C185592680 @default.
• W2042316831 hasConcept C2775910092 @default.
• W2042316831 hasConcept C2777504413 @default.
• W2042316831 hasConcept C2777951760 @default.
• W2042316831 hasConcept C2778108375 @default.
• W2042316831 hasConcept C2778395965 @default.
• W2042316831 hasConcept C2778563252 @default.
• W2042316831 hasConcept C2779377912 @default.
• W2042316831 hasConcept C2780660124 @default.
• W2042316831 hasConcept C2780796126 @default.
• W2042316831 hasConcept C2781403372 @default.
• W2042316831 hasConcept C33789571 @default.
• W2042316831 hasConcept C49039625 @default.
• W2042316831 hasConcept C55493867 @default.
• W2042316831 hasConcept C56191518 @default.
• W2042316831 hasConcept C71315377 @default.
• W2042316831 hasConcept C71924100 @default.
• W2042316831 hasConcept C86803240 @default.
• W2042316831 hasConcept C93984277 @default.
• W2042316831 hasConceptScore W2042316831C1122143 @default.
• W2042316831 hasConceptScore W2042316831C118303440 @default.
• W2042316831 hasConceptScore W2042316831C126322002 @default.
• W2042316831 hasConceptScore W2042316831C134018914 @default.
• W2042316831 hasConceptScore W2042316831C170493617 @default.
• W2042316831 hasConceptScore W2042316831C185592680 @default.
• W2042316831 hasConceptScore W2042316831C2775910092 @default.
• W2042316831 hasConceptScore W2042316831C2777504413 @default.
• W2042316831 hasConceptScore W2042316831C2777951760 @default.
• W2042316831 hasConceptScore W2042316831C2778108375 @default.
• W2042316831 hasConceptScore W2042316831C2778395965 @default.
• W2042316831 hasConceptScore W2042316831C2778563252 @default.
• W2042316831 hasConceptScore W2042316831C2779377912 @default.
• W2042316831 hasConceptScore W2042316831C2780660124 @default.
• W2042316831 hasConceptScore W2042316831C2780796126 @default.
• W2042316831 hasConceptScore W2042316831C2781403372 @default.
• W2042316831 hasConceptScore W2042316831C33789571 @default.
• W2042316831 hasConceptScore W2042316831C49039625 @default.
• W2042316831 hasConceptScore W2042316831C55493867 @default.
• W2042316831 hasConceptScore W2042316831C56191518 @default.
• W2042316831 hasConceptScore W2042316831C71315377 @default.
• W2042316831 hasConceptScore W2042316831C71924100 @default.
• W2042316831 hasConceptScore W2042316831C86803240 @default.
• W2042316831 hasConceptScore W2042316831C93984277 @default.
• W2042316831 hasIssue "1" @default.
• W2042316831 hasLocation W20423168311 @default.
• W2042316831 hasLocation W20423168312 @default.
• W2042316831 hasLocation W20423168313 @default.
• W2042316831 hasLocation W20423168314 @default.
• W2042316831 hasOpenAccess W2042316831 @default.
• W2042316831 hasPrimaryLocation W20423168311 @default.
• W2042316831 hasRelatedWork W1978602869 @default.
• W2042316831 hasRelatedWork W2000605147 @default.

• next