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- W2042331618 abstract "Summary A series of pyrrolo[2,1- c ][1,4]benzodiazepine N10-C11 amidines has been evaluated for in vitro DNA binding through thermal denaturation studies. Some of these compounds cause a significant increase in melting for calf thymus DNA (eg, 0.7 ± 0.1 °C for 21 ), possibly due to non-covalent interaction with bases positioned on the floor of the minor groove in the DNA duplex." @default.
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- W2042331618 date "1996-01-01" @default.
- W2042331618 modified "2023-09-27" @default.
- W2042331618 title "DNA-binding properties of pyrrolo[2,1-c][1,4]benzodiazepine N10-C11 amidines" @default.
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- W2042331618 doi "https://doi.org/10.1016/0223-5234(96)89167-7" @default.
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