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- W2042340279 endingPage "52" @default.
- W2042340279 startingPage "45" @default.
- W2042340279 abstract "IGFs and their binding proteins have been shown to exhibit both protective and deleterious effects in ocular disease. Recent studies have characterized the expression patterns of different IGFBPs in retinal layers and within the vitreous. IGFBP-3 has roles in vascular protection stimulating proliferation, migration, and differentiation of vascular progenitor cells to sites of injury. IGFBP-3 increases pericyte ensheathment and shows anti-inflammatory effects by reducing microglia activation in diabetes. IGFBP-5 has recently been linked to mediating fibrosis in proliferative vitreoretinopathy but also reduces neovascularization. Thus, the regulatory balance between IGF and IGFBPs can have profound impact on target tissues. This review discusses recent findings of IGF and IGFBP expression in the eye with relevance to different retinopathies." @default.
- W2042340279 created "2016-06-24" @default.
- W2042340279 creator A5028741605 @default.
- W2042340279 creator A5033890071 @default.
- W2042340279 creator A5041346828 @default.
- W2042340279 creator A5045419036 @default.
- W2042340279 creator A5083537513 @default.
- W2042340279 creator A5085495179 @default.
- W2042340279 date "2013-06-01" @default.
- W2042340279 modified "2023-09-26" @default.
- W2042340279 title "An ocular view of the IGF–IGFBP system" @default.
- W2042340279 cites W1588516858 @default.
- W2042340279 cites W1964214896 @default.
- W2042340279 cites W1964625898 @default.
- W2042340279 cites W1970276807 @default.
- W2042340279 cites W1970754801 @default.
- W2042340279 cites W1972255467 @default.
- W2042340279 cites W1972975078 @default.
- W2042340279 cites W1975636367 @default.
- W2042340279 cites W1976272429 @default.
- W2042340279 cites W1977664250 @default.
- W2042340279 cites W1978025072 @default.
- W2042340279 cites W1979886434 @default.
- W2042340279 cites W1983031528 @default.
- W2042340279 cites W1984024821 @default.
- W2042340279 cites W1985856548 @default.
- W2042340279 cites W1989807476 @default.
- W2042340279 cites W1990439069 @default.
- W2042340279 cites W1995611494 @default.
- W2042340279 cites W1995633498 @default.
- W2042340279 cites W1996029988 @default.
- W2042340279 cites W1998641293 @default.
- W2042340279 cites W2000900558 @default.
- W2042340279 cites W2001685355 @default.
- W2042340279 cites W2003115793 @default.
- W2042340279 cites W2006027984 @default.
- W2042340279 cites W2006377760 @default.
- W2042340279 cites W2007006137 @default.
- W2042340279 cites W2008618426 @default.
- W2042340279 cites W2009237402 @default.
- W2042340279 cites W2010363122 @default.
- W2042340279 cites W2012505775 @default.
- W2042340279 cites W2014793666 @default.
- W2042340279 cites W2016124553 @default.
- W2042340279 cites W2016742796 @default.
- W2042340279 cites W2017140546 @default.
- W2042340279 cites W2019329034 @default.
- W2042340279 cites W2021350314 @default.
- W2042340279 cites W2021429468 @default.
- W2042340279 cites W2023353015 @default.
- W2042340279 cites W2027469471 @default.
- W2042340279 cites W2028080517 @default.
- W2042340279 cites W2030550361 @default.
- W2042340279 cites W2034079364 @default.
- W2042340279 cites W2036545146 @default.
- W2042340279 cites W2036872904 @default.
- W2042340279 cites W2038683364 @default.
- W2042340279 cites W2041888883 @default.
- W2042340279 cites W2042704812 @default.
- W2042340279 cites W2045156186 @default.
- W2042340279 cites W2046966014 @default.
- W2042340279 cites W2050411677 @default.
- W2042340279 cites W2051214153 @default.
- W2042340279 cites W2051266804 @default.
- W2042340279 cites W2052356702 @default.
- W2042340279 cites W2052737983 @default.
- W2042340279 cites W2053401836 @default.
- W2042340279 cites W2056333138 @default.
- W2042340279 cites W2058196624 @default.
- W2042340279 cites W2061624989 @default.
- W2042340279 cites W2064147974 @default.
- W2042340279 cites W2065414187 @default.
- W2042340279 cites W2067192388 @default.
- W2042340279 cites W2070696872 @default.
- W2042340279 cites W2077722928 @default.
- W2042340279 cites W2077956417 @default.
- W2042340279 cites W2079373283 @default.
- W2042340279 cites W2080786018 @default.
- W2042340279 cites W2082805730 @default.
- W2042340279 cites W2083166896 @default.
- W2042340279 cites W2087010578 @default.
- W2042340279 cites W2090291588 @default.
- W2042340279 cites W2090496521 @default.
- W2042340279 cites W2091678536 @default.
- W2042340279 cites W2094042342 @default.
- W2042340279 cites W2094777477 @default.
- W2042340279 cites W2097213635 @default.
- W2042340279 cites W2100649605 @default.
- W2042340279 cites W2102123572 @default.
- W2042340279 cites W2106527155 @default.
- W2042340279 cites W2107029521 @default.
- W2042340279 cites W2113936086 @default.
- W2042340279 cites W2115956365 @default.
- W2042340279 cites W2117203493 @default.
- W2042340279 cites W2117422863 @default.
- W2042340279 cites W2119906430 @default.
- W2042340279 cites W2123328228 @default.
- W2042340279 cites W2124824608 @default.