Matches in SemOpenAlex for { <https://semopenalex.org/work/W2042367182> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2042367182 abstract "Geneticists in Cambridge, UK, are setting up one of Europe's most advanced centers for studying how genes are expressed in the fruit fly Drosophila melanogaster. The center will compare DNA samples from the 70 or so fly laboratories around the UK, or elsewhere, with stored fragments of the Drosophila genome, some of which contain carefully constructed mutations, to provide exquisitely sensitive profiles of gene expression. The profiles will detail which genes are expressed, when and under what conditions. They will allow researchers to look for changes in gene expression that occur, for example, over a particular developmental period or as a result of some mutation. At the heart of the center is a robotic production line that turns out microarrays spotted with samples of Drosophila DNA. Researchers will be able to use the facility like a ‘black box,’ says Steve Russell, leader of the group running the UK Drosophila Functional Genomics Facility at the University of Cambridge ‘But we will also be offering training on the use of these technologies’.A related proteomics facility, also funded out of the £3.5 million grant from the Biotechnology and Biological Sciences Research Council (BBSRC) being used to establish the genomics site, will similarly identify and classify proteins derived from the Drosophila genome. The proteomics facility will also support geneticists working on Arabidopsis, a widely used plant model organism. The center plans to make all its genomics and proteomics data freely accessible on the Web, as and when the information becomes available. It is also developing open-source software, in collaboration with physicists and mathematicians, to analyze the huge volume of data that the project will produce. Russell says the center aims to broaden its links to other fly laboratories around the world to develop more comprehensive arrays. Its current arrays were developed using a collection of Drosophila cDNAs created by the Berkeley Drosophila Genome Project." @default.
- W2042367182 created "2016-06-24" @default.
- W2042367182 creator A5014596655 @default.
- W2042367182 date "2001-01-01" @default.
- W2042367182 modified "2023-09-27" @default.
- W2042367182 title "Advanced genomics promise fruit fly exposure" @default.
- W2042367182 doi "https://doi.org/10.1016/s0962-8924(00)01888-2" @default.
- W2042367182 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11146285" @default.
- W2042367182 hasPublicationYear "2001" @default.
- W2042367182 type Work @default.
- W2042367182 sameAs 2042367182 @default.
- W2042367182 citedByCount "0" @default.
- W2042367182 crossrefType "journal-article" @default.
- W2042367182 hasAuthorship W2042367182A5014596655 @default.
- W2042367182 hasConcept C104317684 @default.
- W2042367182 hasConcept C141231307 @default.
- W2042367182 hasConcept C143065580 @default.
- W2042367182 hasConcept C150194340 @default.
- W2042367182 hasConcept C161078062 @default.
- W2042367182 hasConcept C189206191 @default.
- W2042367182 hasConcept C2776041557 @default.
- W2042367182 hasConcept C2779491563 @default.
- W2042367182 hasConcept C2780104201 @default.
- W2042367182 hasConcept C46111723 @default.
- W2042367182 hasConcept C54355233 @default.
- W2042367182 hasConcept C70721500 @default.
- W2042367182 hasConcept C86803240 @default.
- W2042367182 hasConcept C95371953 @default.
- W2042367182 hasConceptScore W2042367182C104317684 @default.
- W2042367182 hasConceptScore W2042367182C141231307 @default.
- W2042367182 hasConceptScore W2042367182C143065580 @default.
- W2042367182 hasConceptScore W2042367182C150194340 @default.
- W2042367182 hasConceptScore W2042367182C161078062 @default.
- W2042367182 hasConceptScore W2042367182C189206191 @default.
- W2042367182 hasConceptScore W2042367182C2776041557 @default.
- W2042367182 hasConceptScore W2042367182C2779491563 @default.
- W2042367182 hasConceptScore W2042367182C2780104201 @default.
- W2042367182 hasConceptScore W2042367182C46111723 @default.
- W2042367182 hasConceptScore W2042367182C54355233 @default.
- W2042367182 hasConceptScore W2042367182C70721500 @default.
- W2042367182 hasConceptScore W2042367182C86803240 @default.
- W2042367182 hasConceptScore W2042367182C95371953 @default.
- W2042367182 hasLocation W20423671821 @default.
- W2042367182 hasLocation W20423671822 @default.
- W2042367182 hasOpenAccess W2042367182 @default.
- W2042367182 hasPrimaryLocation W20423671821 @default.
- W2042367182 hasRelatedWork W108939970 @default.
- W2042367182 hasRelatedWork W1509642782 @default.
- W2042367182 hasRelatedWork W1902389595 @default.
- W2042367182 hasRelatedWork W1969080837 @default.
- W2042367182 hasRelatedWork W1974626349 @default.
- W2042367182 hasRelatedWork W2002714061 @default.
- W2042367182 hasRelatedWork W2017568996 @default.
- W2042367182 hasRelatedWork W2022796482 @default.
- W2042367182 hasRelatedWork W2039841865 @default.
- W2042367182 hasRelatedWork W2068018762 @default.
- W2042367182 hasRelatedWork W2073145979 @default.
- W2042367182 hasRelatedWork W2125114313 @default.
- W2042367182 hasRelatedWork W2228473711 @default.
- W2042367182 hasRelatedWork W2395068850 @default.
- W2042367182 hasRelatedWork W2403159261 @default.
- W2042367182 hasRelatedWork W2900170213 @default.
- W2042367182 hasRelatedWork W3106121751 @default.
- W2042367182 hasRelatedWork W3128201321 @default.
- W2042367182 hasRelatedWork W85140839 @default.
- W2042367182 hasRelatedWork W2353144466 @default.
- W2042367182 isParatext "false" @default.
- W2042367182 isRetracted "false" @default.
- W2042367182 magId "2042367182" @default.
- W2042367182 workType "article" @default.