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• W2042374941 abstract "Norepinephrine-rich cell suspensions, prepared from the locus coeruleus region of rat fetuses, were grafted bilaterally into the hippocampus of rats made hypersensitive to hippocampal kindling by a neurotoxic lesion of the central catecholamine system. The animals with grafts showed a marked suppression of the onset and progression of kindling-induced epilepsy, and this effect was correlated with the degree of graft-derived noradrenergic innervation of the host hippocampal formation. We conclude that grafted neurons can modulate the excitability of epileptic brain regions." @default.
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• W2042374941 date "1987-12-01" @default.
• W2042374941 modified "2023-10-03" @default.
• W2042374941 title "Grafted noradrenergic neurons suppress seizure development in kindling-induced epilepsy." @default.
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• W2042374941 doi "https://doi.org/10.1073/pnas.84.23.8712" @default.
• W2042374941 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/299616" @default.
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