FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2042421846> ?p ?o ?g. }

• W2042421846 endingPage "1395" @default.
• W2042421846 startingPage "1395" @default.
• W2042421846 abstract "Mr. P.M. Tromans and others (February 28 p. 679) found that estradiol applied vaginally was a safe and effective method for ripening the unfavorable cervix prior to induction of labor. Before estradiol is used generally for this purpose we would like to call attention to a possible side effect of estradiol that we have observed in the babies--namely neonatal hyperbilirubinemia during the 1st week of life. In a double-blind prospective study of 50 primiparous women with a Bishop score below 5 we investigated the effect of estradiol on induction of labor and cervical ripening. In 25 women 115 mg 17beta-estradiol was instilled into the extraamniotic space (estradiol group) through a Foley catheter with 40 ml water in the balloon. The catheter was left in utero after the instillation. In the remaining 25 women a sterile 0.9% saline solution was instilled (saline group). Otherwise the procedure was the same. After the instillation all women took oxytocin tablets every 30 minutes for 5 hours. 18 hours after instillation (next morning) delivery was completed in 15 women in the estradiol group and 17 women in the saline group; in the rest of the women the median Bishop score was 7.5 in both groups. A significant rise in the serum concentration of estradiol was seen in the women in the estradiol group and during the hours after the instillation the serum concentrations of estradiol were significantly higher in the estradiol group than in the saline group. Serum concentrations of estradiol in the umbilical veins at the time of birth were the same in the 2 groups. Phototherapy was given to 13 infants in the estradiol group and 4 infants in the saline group because of neonatal hyperbilirubinemia (serum bilirubin >200 mcmol/l (11.7 mg/100 ml) during the 1st week of life). The observed difference between the groups may be due to random variation but the possibility of that is less than 0.02 (Fishers exact test 2-tailed). We therefore think that this possible connection between estradiol and neonatal hyperbilirubinemia should be investigated further in controlled clinical trials before estradiol is suggested as a safe drug for cervical ripening. (Authors modified)" @default.
• W2042421846 created "2016-06-24" @default.
• W2042421846 creator A5019508696 @default.
• W2042421846 creator A5075119273 @default.
• W2042421846 creator A5090328030 @default.
• W2042421846 date "1981-04-25" @default.
• W2042421846 modified "2023-09-26" @default.
• W2042421846 title "Comparison of oestradiol and prostaglandin E2 vaginal gel for ripening the unfavourable cervix" @default.
• W2042421846 cites W1975730386 @default.
• W2042421846 cites W2050432297 @default.
• W2042421846 doi "https://doi.org/10.1136/bmj.282.6273.1395-a" @default.
• W2042421846 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1504984" @default.
• W2042421846 hasPublicationYear "1981" @default.
• W2042421846 type Work @default.
• W2042421846 sameAs 2042421846 @default.
• W2042421846 citedByCount "3" @default.
• W2042421846 crossrefType "journal-article" @default.
• W2042421846 hasAuthorship W2042421846A5019508696 @default.
• W2042421846 hasAuthorship W2042421846A5075119273 @default.
• W2042421846 hasAuthorship W2042421846A5090328030 @default.
• W2042421846 hasBestOaLocation W20424218462 @default.
• W2042421846 hasConcept C121608353 @default.
• W2042421846 hasConcept C126322002 @default.
• W2042421846 hasConcept C131872663 @default.
• W2042421846 hasConcept C134018914 @default.
• W2042421846 hasConcept C16685009 @default.
• W2042421846 hasConcept C172353545 @default.
• W2042421846 hasConcept C185592680 @default.
• W2042421846 hasConcept C2777740455 @default.
• W2042421846 hasConcept C2777956040 @default.
• W2042421846 hasConcept C29456083 @default.
• W2042421846 hasConcept C31903555 @default.
• W2042421846 hasConcept C41008148 @default.
• W2042421846 hasConcept C71924100 @default.
• W2042421846 hasConceptScore W2042421846C121608353 @default.
• W2042421846 hasConceptScore W2042421846C126322002 @default.
• W2042421846 hasConceptScore W2042421846C131872663 @default.
• W2042421846 hasConceptScore W2042421846C134018914 @default.
• W2042421846 hasConceptScore W2042421846C16685009 @default.
• W2042421846 hasConceptScore W2042421846C172353545 @default.
• W2042421846 hasConceptScore W2042421846C185592680 @default.
• W2042421846 hasConceptScore W2042421846C2777740455 @default.
• W2042421846 hasConceptScore W2042421846C2777956040 @default.
• W2042421846 hasConceptScore W2042421846C29456083 @default.
• W2042421846 hasConceptScore W2042421846C31903555 @default.
• W2042421846 hasConceptScore W2042421846C41008148 @default.
• W2042421846 hasConceptScore W2042421846C71924100 @default.
• W2042421846 hasIssue "6273" @default.
• W2042421846 hasLocation W20424218461 @default.
• W2042421846 hasLocation W20424218462 @default.
• W2042421846 hasLocation W20424218463 @default.
• W2042421846 hasOpenAccess W2042421846 @default.
• W2042421846 hasPrimaryLocation W20424218461 @default.
• W2042421846 hasRelatedWork W1542718233 @default.
• W2042421846 hasRelatedWork W2009002544 @default.
• W2042421846 hasRelatedWork W2015637469 @default.
• W2042421846 hasRelatedWork W2041335310 @default.
• W2042421846 hasRelatedWork W2047662229 @default.
• W2042421846 hasRelatedWork W2065259624 @default.
• W2042421846 hasRelatedWork W2407865695 @default.
• W2042421846 hasRelatedWork W2418294786 @default.
• W2042421846 hasRelatedWork W2432671853 @default.
• W2042421846 hasRelatedWork W2435290033 @default.
• W2042421846 hasVolume "282" @default.
• W2042421846 isParatext "false" @default.
• W2042421846 isRetracted "false" @default.
• W2042421846 magId "2042421846" @default.
• W2042421846 workType "article" @default.