FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2042456930> ?p ?o ?g. }

• W2042456930 endingPage "227" @default.
• W2042456930 startingPage "219" @default.
• W2042456930 abstract "Summary We assessed whether complement and its factor C4 or abnormal immunoglobulin levels are associated with chronic or recurrent rhinosinusitis. We used multiple patient and control groups to obtain clinically meaningful data. Adult chronic or recurrent rhinosinusitis and acute purulent rhinosinusitis patients were compared with unselected adults and controls without previous rhinosinusitis. Associated clinical factors were reviewed. Levels of immunoglobulins, plasma C3, C4 and classical pathway haemolytic activity were analysed. C4 immunophenotyping was used to detect C4A and C4B deficiencies as null alleles. Complement was up-regulated in rhinosinusitis. C4A nulls and low IgA, IgG, IgG1, IgG2, IgG3 and IgG4 levels were all more common in chronic or recurrent rhinosinusitis patients than in unselected and healthy controls. We searched for relevant differences between the patient groups. According to stepwise logistic regression analysis, nasal polyposis [odds ratio (OR) 10·64, 95% confidence interval (CI) 2·5–45·7, P = 0·001], bronchial asthma (OR 8.87, 95% CI 2·3–34·9, P = 0·002), C4A null alleles (OR 5·84, 95% CI 1·4–24·9, P = 0·017) and low levels of IgG4 together with either IgG1 or IgG2 (OR 15·25, 95% CI 1·4–166·8, P = 0·026) were more common in chronic or recurrent rhinosinusitis than in acute rhinosinusitis patients. Isolated low IgG subclasses had limited value in patient assessment. C4A null alleles are associated with chronic or recurrent rhinosinusitis, potentially through their effect on immune defence and inflammation control. Multiple clinical and immunological parameters may need to be evaluated when searching for prognostic variables." @default.
• W2042456930 created "2016-06-24" @default.
• W2042456930 creator A5002029171 @default.
• W2042456930 creator A5023823125 @default.
• W2042456930 creator A5025820462 @default.
• W2042456930 creator A5026241120 @default.
• W2042456930 creator A5030409553 @default.
• W2042456930 creator A5048561201 @default.
• W2042456930 creator A5051872714 @default.
• W2042456930 creator A5063828781 @default.
• W2042456930 creator A5065050544 @default.
• W2042456930 creator A5070558349 @default.
• W2042456930 creator A5083971519 @default.
• W2042456930 date "2006-06-23" @default.
• W2042456930 modified "2023-10-14" @default.
• W2042456930 title "Immunoglobulins and complement factor C4 in adult rhinosinusitis" @default.
• W2042456930 cites W149987944 @default.
• W2042456930 cites W1543650651 @default.
• W2042456930 cites W1950734237 @default.
• W2042456930 cites W1966690397 @default.
• W2042456930 cites W1972758421 @default.
• W2042456930 cites W1973374323 @default.
• W2042456930 cites W1977598581 @default.
• W2042456930 cites W1980219722 @default.
• W2042456930 cites W1984699700 @default.
• W2042456930 cites W1985240611 @default.
• W2042456930 cites W1985474124 @default.
• W2042456930 cites W1986964580 @default.
• W2042456930 cites W1995978242 @default.
• W2042456930 cites W1999169778 @default.
• W2042456930 cites W2000319686 @default.
• W2042456930 cites W2002276775 @default.
• W2042456930 cites W2002944993 @default.
• W2042456930 cites W2008541844 @default.
• W2042456930 cites W2025928313 @default.
• W2042456930 cites W2027541022 @default.
• W2042456930 cites W2032391564 @default.
• W2042456930 cites W2035365044 @default.
• W2042456930 cites W2036264090 @default.
• W2042456930 cites W2043993805 @default.
• W2042456930 cites W2050656150 @default.
• W2042456930 cites W2051850052 @default.
• W2042456930 cites W2054359284 @default.
• W2042456930 cites W2066226017 @default.
• W2042456930 cites W2070527591 @default.
• W2042456930 cites W2082558728 @default.
• W2042456930 cites W2082975743 @default.
• W2042456930 cites W2086375085 @default.
• W2042456930 cites W2094200300 @default.
• W2042456930 cites W2100021952 @default.
• W2042456930 cites W2104436632 @default.
• W2042456930 cites W2105671517 @default.
• W2042456930 cites W2107859864 @default.
• W2042456930 cites W2120575544 @default.
• W2042456930 cites W2129620820 @default.
• W2042456930 cites W2129646517 @default.
• W2042456930 cites W2129761445 @default.
• W2042456930 cites W2133048859 @default.
• W2042456930 cites W2145710378 @default.
• W2042456930 cites W2147438174 @default.
• W2042456930 cites W2167381898 @default.
• W2042456930 cites W2314156670 @default.
• W2042456930 cites W2317746841 @default.
• W2042456930 cites W2417407007 @default.
• W2042456930 cites W2468202420 @default.
• W2042456930 cites W27883885 @default.
• W2042456930 cites W315197452 @default.
• W2042456930 cites W63326701 @default.
• W2042456930 cites W2318948795 @default.
• W2042456930 doi "https://doi.org/10.1111/j.1365-2249.2006.03134.x" @default.
• W2042456930 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1809671" @default.
• W2042456930 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16879240" @default.
• W2042456930 hasPublicationYear "2006" @default.
• W2042456930 type Work @default.
• W2042456930 sameAs 2042456930 @default.
• W2042456930 citedByCount "46" @default.
• W2042456930 countsByYear W20424569302012 @default.
• W2042456930 countsByYear W20424569302013 @default.
• W2042456930 countsByYear W20424569302014 @default.
• W2042456930 countsByYear W20424569302015 @default.
• W2042456930 countsByYear W20424569302016 @default.
• W2042456930 countsByYear W20424569302017 @default.
• W2042456930 countsByYear W20424569302018 @default.
• W2042456930 countsByYear W20424569302019 @default.
• W2042456930 countsByYear W20424569302020 @default.
• W2042456930 countsByYear W20424569302021 @default.
• W2042456930 countsByYear W20424569302023 @default.
• W2042456930 crossrefType "journal-article" @default.
• W2042456930 hasAuthorship W2042456930A5002029171 @default.
• W2042456930 hasAuthorship W2042456930A5023823125 @default.
• W2042456930 hasAuthorship W2042456930A5025820462 @default.
• W2042456930 hasAuthorship W2042456930A5026241120 @default.
• W2042456930 hasAuthorship W2042456930A5030409553 @default.
• W2042456930 hasAuthorship W2042456930A5048561201 @default.
• W2042456930 hasAuthorship W2042456930A5051872714 @default.
• W2042456930 hasAuthorship W2042456930A5063828781 @default.
• W2042456930 hasAuthorship W2042456930A5065050544 @default.
• W2042456930 hasAuthorship W2042456930A5070558349 @default.

• next