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• W2042461971 abstract "Conventional forms of administrations of nonabsorbable drugs and peptides rely on their parenteral injection. The intestinal epithelium represents the major barrier to the oral absorption of these therapeutical agents into the systemic circulation. Recently, a number of innovative drug delivery approaches have been developed, including the drug entrapment within small vesicles or their passage through the intestinal paracellular pathway. Zonula occludens toxin, a recently discovered protein elaborated byVibrio cholerae,provided tools for gaining more insights on the pathophysiology of the regulation of intestinal permeability and to developing alternative approaches for the oral delivery of drugs and macromolecules normally not absorbed through the intestine." @default.
• W2042461971 created "2016-06-24" @default.
• W2042461971 creator A5046930712 @default.
• W2042461971 date "1998-05-01" @default.
• W2042461971 modified "2023-09-23" @default.
• W2042461971 title "Modulation of Intestinal Permeability: An Innovative Method of Oral Drug Delivery for the Treatment of Inherited and Acquired Human Diseases" @default.
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• W2042461971 doi "https://doi.org/10.1006/mgme.1998.2667" @default.
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