FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2042475444> ?p ?o ?g. }

• W2042475444 endingPage "550" @default.
• W2042475444 startingPage "545" @default.
• W2042475444 abstract "Messenger RNA from rat liver was translated in a micrococcal-nuclease-treated reticulocyte lysate supplemented with liver tRNA. Synthesis of the liver proteins haemopexin, ferritin and albumin was analyzed by quantitative immunoprecipitation. The relative translation yield of these proteins changed as a function of the amount of mRNA present during protein synthesis, revealing the existence of translational competition between individual species of mRNA from the liver. The results show that the mRNA species encoding haemopexin, ferritin and albumin possess distinctly different abilities to compete for one or more critical components in translation, with competitive strength increasing in this order. Although on a weight basis total liver mRNA is apparently as effective a template for protein synthesis as is globin mRNA, the latter displays a greater resistance to inhibition of its translation by KCl. In analogy with the translation properties of α-globin and β-globin mRNA [Di Segni, G., Rosen, H. and Kaempfer, R. (1979) Biochemistry, 18, 2847–2854], this finding suggests that globin mRNA possesses greater competitive strength than does total liver mRNA. Increasing amounts of globin mRNA competitively inhibit the translation of albumin and ferritin mRNA present in total liver mRNA. The competition is relived by the addition of eukaryotic initiation factor eIF-2. Translation of ferritin mRNA responds more vigorously to relief by eIF-2 than does translation of albumin mRNA, a finding consistent with the observation that albumin mRNA competes more effectively than ferritin mRNA in translation. The results support the assumption that albumin mRNA possesses a greater affinity for eIF-2 than does ferritin mRNA." @default.
• W2042475444 created "2016-06-24" @default.
• W2042475444 creator A5005090633 @default.
• W2042475444 creator A5012505186 @default.
• W2042475444 date "1983-04-01" @default.
• W2042475444 modified "2023-09-27" @default.
• W2042475444 title "Translational Competition by mRNA Species Encoding Albumin, Ferritin, Haemopexin and Globin" @default.
• W2042475444 cites W1485792634 @default.
• W2042475444 cites W1501701594 @default.
• W2042475444 cites W1508904094 @default.
• W2042475444 cites W1519918229 @default.
• W2042475444 cites W1520047720 @default.
• W2042475444 cites W1522423422 @default.
• W2042475444 cites W1529401899 @default.
• W2042475444 cites W1535298471 @default.
• W2042475444 cites W1541082414 @default.
• W2042475444 cites W1966218780 @default.
• W2042475444 cites W1968656226 @default.
• W2042475444 cites W1970403529 @default.
• W2042475444 cites W1984156496 @default.
• W2042475444 cites W1993034545 @default.
• W2042475444 cites W1995135269 @default.
• W2042475444 cites W1997142408 @default.
• W2042475444 cites W2005089186 @default.
• W2042475444 cites W2040393821 @default.
• W2042475444 cites W2043935052 @default.
• W2042475444 cites W2051686057 @default.
• W2042475444 cites W2052740275 @default.
• W2042475444 cites W2060044205 @default.
• W2042475444 cites W2071979967 @default.
• W2042475444 cites W2074398119 @default.
• W2042475444 cites W2081071291 @default.
• W2042475444 cites W2087942186 @default.
• W2042475444 cites W2089113264 @default.
• W2042475444 cites W2092253073 @default.
• W2042475444 cites W2095353074 @default.
• W2042475444 cites W2096152825 @default.
• W2042475444 cites W2098353733 @default.
• W2042475444 cites W2131490420 @default.
• W2042475444 cites W2169255375 @default.
• W2042475444 cites W2409840855 @default.
• W2042475444 cites W2412805471 @default.
• W2042475444 cites W348510383 @default.
• W2042475444 cites W4242506637 @default.
• W2042475444 doi "https://doi.org/10.1111/j.1432-1033.1983.tb07296.x" @default.
• W2042475444 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6840065" @default.
• W2042475444 hasPublicationYear "1983" @default.
• W2042475444 type Work @default.
• W2042475444 sameAs 2042475444 @default.
• W2042475444 citedByCount "22" @default.
• W2042475444 crossrefType "journal-article" @default.
• W2042475444 hasAuthorship W2042475444A5005090633 @default.
• W2042475444 hasAuthorship W2042475444A5012505186 @default.
• W2042475444 hasConcept C104317684 @default.
• W2042475444 hasConcept C105580179 @default.
• W2042475444 hasConcept C125996951 @default.
• W2042475444 hasConcept C149364088 @default.
• W2042475444 hasConcept C153911025 @default.
• W2042475444 hasConcept C162419368 @default.
• W2042475444 hasConcept C2776125364 @default.
• W2042475444 hasConcept C2778319317 @default.
• W2042475444 hasConcept C2778403015 @default.
• W2042475444 hasConcept C3675279 @default.
• W2042475444 hasConcept C55493867 @default.
• W2042475444 hasConcept C86803240 @default.
• W2042475444 hasConceptScore W2042475444C104317684 @default.
• W2042475444 hasConceptScore W2042475444C105580179 @default.
• W2042475444 hasConceptScore W2042475444C125996951 @default.
• W2042475444 hasConceptScore W2042475444C149364088 @default.
• W2042475444 hasConceptScore W2042475444C153911025 @default.
• W2042475444 hasConceptScore W2042475444C162419368 @default.
• W2042475444 hasConceptScore W2042475444C2776125364 @default.
• W2042475444 hasConceptScore W2042475444C2778319317 @default.
• W2042475444 hasConceptScore W2042475444C2778403015 @default.
• W2042475444 hasConceptScore W2042475444C3675279 @default.
• W2042475444 hasConceptScore W2042475444C55493867 @default.
• W2042475444 hasConceptScore W2042475444C86803240 @default.
• W2042475444 hasIssue "3" @default.
• W2042475444 hasLocation W20424754441 @default.
• W2042475444 hasLocation W20424754442 @default.
• W2042475444 hasOpenAccess W2042475444 @default.
• W2042475444 hasPrimaryLocation W20424754441 @default.
• W2042475444 hasRelatedWork W1502026043 @default.
• W2042475444 hasRelatedWork W1968284764 @default.
• W2042475444 hasRelatedWork W2004908172 @default.
• W2042475444 hasRelatedWork W2006783732 @default.
• W2042475444 hasRelatedWork W2042475444 @default.
• W2042475444 hasRelatedWork W2054807848 @default.
• W2042475444 hasRelatedWork W2088967333 @default.
• W2042475444 hasRelatedWork W323610533 @default.
• W2042475444 hasRelatedWork W1982382664 @default.
• W2042475444 hasRelatedWork W2071395481 @default.
• W2042475444 hasVolume "131" @default.
• W2042475444 isParatext "false" @default.
• W2042475444 isRetracted "false" @default.
• W2042475444 magId "2042475444" @default.
• W2042475444 workType "article" @default.