Matches in SemOpenAlex for { <https://semopenalex.org/work/W2042487309> ?p ?o ?g. }
- W2042487309 abstract "To determine the spatial distribution of cortical and subcortical volume loss in patients with diffuse traumatic axonal injury and to assess the relationship between regional atrophy and functional outcome.Prospective imaging study. Longitudinal changes in global and regional brain volumes were assessed using high-resolution magnetic resonance imaging-based morphometric analysis.Inpatient traumatic brain injury unit.Twenty-five patients with diffuse traumatic axonal injury and 22 age- and sex-matched controls.Changes in global and regional brain volumes between initial and follow-up magnetic resonance imaging were used to assess the spatial distribution of posttraumatic volume loss. The Glasgow Outcome Scale-Extended score was the primary measure of functional outcome.Patients underwent substantial global atrophy with mean whole-brain parenchymal volume loss of 4.5% (95% confidence interval, 2.7%-6.3%). Decreases in volume (at a false discovery rate of 0.05) were seen in several brain regions including the amygdala, hippocampus, thalamus, corpus callosum, putamen, precuneus, postcentral gyrus, paracentral lobule, and parietal and frontal cortices, while other regions such as the caudate and inferior temporal cortex were relatively resistant to atrophy. Loss of whole-brain parenchymal volume was predictive of long-term disability, as was atrophy of particular brain regions including the inferior parietal cortex, pars orbitalis, pericalcarine cortex, and supramarginal gyrus.Traumatic axonal injury leads to substantial posttraumatic atrophy that is regionally selective rather than diffuse, and volume loss in certain regions may have prognostic value for functional recovery." @default.
- W2042487309 created "2016-06-24" @default.
- W2042487309 creator A5003651343 @default.
- W2042487309 creator A5003966683 @default.
- W2042487309 creator A5026164013 @default.
- W2042487309 creator A5028980008 @default.
- W2042487309 creator A5029617270 @default.
- W2042487309 creator A5045466607 @default.
- W2042487309 creator A5056323628 @default.
- W2042487309 creator A5068741363 @default.
- W2042487309 creator A5070439658 @default.
- W2042487309 creator A5072570457 @default.
- W2042487309 creator A5078849304 @default.
- W2042487309 creator A5083610730 @default.
- W2042487309 creator A5088324489 @default.
- W2042487309 date "2010-07-01" @default.
- W2042487309 modified "2023-10-17" @default.
- W2042487309 title "Regionally Selective Atrophy After Traumatic Axonal Injury" @default.
- W2042487309 cites W1583631062 @default.
- W2042487309 cites W1972969270 @default.
- W2042487309 cites W1977045648 @default.
- W2042487309 cites W1988366576 @default.
- W2042487309 cites W1989229423 @default.
- W2042487309 cites W1993812357 @default.
- W2042487309 cites W1999857562 @default.
- W2042487309 cites W2004293194 @default.
- W2042487309 cites W2005561082 @default.
- W2042487309 cites W2008552409 @default.
- W2042487309 cites W2009105636 @default.
- W2042487309 cites W2014930223 @default.
- W2042487309 cites W2027928004 @default.
- W2042487309 cites W2038862135 @default.
- W2042487309 cites W2055504658 @default.
- W2042487309 cites W2063841819 @default.
- W2042487309 cites W2064036287 @default.
- W2042487309 cites W2071138914 @default.
- W2042487309 cites W2072058015 @default.
- W2042487309 cites W2075061360 @default.
- W2042487309 cites W2084817972 @default.
- W2042487309 cites W2087170847 @default.
- W2042487309 cites W2088858548 @default.
- W2042487309 cites W2089531918 @default.
- W2042487309 cites W2092599527 @default.
- W2042487309 cites W2097394664 @default.
- W2042487309 cites W2098939947 @default.
- W2042487309 cites W2110208125 @default.
- W2042487309 cites W2113319997 @default.
- W2042487309 cites W2114522289 @default.
- W2042487309 cites W2126081763 @default.
- W2042487309 cites W2134547791 @default.
- W2042487309 cites W2134785535 @default.
- W2042487309 cites W2136518352 @default.
- W2042487309 cites W2151721316 @default.
- W2042487309 cites W2158592797 @default.
- W2042487309 cites W2159806977 @default.
- W2042487309 cites W2168767889 @default.
- W2042487309 cites W2620344835 @default.
- W2042487309 cites W2736091234 @default.
- W2042487309 doi "https://doi.org/10.1001/archneurol.2010.149" @default.
- W2042487309 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3465162" @default.
- W2042487309 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20625067" @default.
- W2042487309 hasPublicationYear "2010" @default.
- W2042487309 type Work @default.
- W2042487309 sameAs 2042487309 @default.
- W2042487309 citedByCount "123" @default.
- W2042487309 countsByYear W20424873092012 @default.
- W2042487309 countsByYear W20424873092013 @default.
- W2042487309 countsByYear W20424873092014 @default.
- W2042487309 countsByYear W20424873092015 @default.
- W2042487309 countsByYear W20424873092016 @default.
- W2042487309 countsByYear W20424873092017 @default.
- W2042487309 countsByYear W20424873092018 @default.
- W2042487309 countsByYear W20424873092019 @default.
- W2042487309 countsByYear W20424873092020 @default.
- W2042487309 countsByYear W20424873092021 @default.
- W2042487309 countsByYear W20424873092022 @default.
- W2042487309 countsByYear W20424873092023 @default.
- W2042487309 crossrefType "journal-article" @default.
- W2042487309 hasAuthorship W2042487309A5003651343 @default.
- W2042487309 hasAuthorship W2042487309A5003966683 @default.
- W2042487309 hasAuthorship W2042487309A5026164013 @default.
- W2042487309 hasAuthorship W2042487309A5028980008 @default.
- W2042487309 hasAuthorship W2042487309A5029617270 @default.
- W2042487309 hasAuthorship W2042487309A5045466607 @default.
- W2042487309 hasAuthorship W2042487309A5056323628 @default.
- W2042487309 hasAuthorship W2042487309A5068741363 @default.
- W2042487309 hasAuthorship W2042487309A5070439658 @default.
- W2042487309 hasAuthorship W2042487309A5072570457 @default.
- W2042487309 hasAuthorship W2042487309A5078849304 @default.
- W2042487309 hasAuthorship W2042487309A5083610730 @default.
- W2042487309 hasAuthorship W2042487309A5088324489 @default.
- W2042487309 hasBestOaLocation W20424873091 @default.
- W2042487309 hasConcept C118552586 @default.
- W2042487309 hasConcept C126322002 @default.
- W2042487309 hasConcept C126838900 @default.
- W2042487309 hasConcept C142724271 @default.
- W2042487309 hasConcept C143409427 @default.
- W2042487309 hasConcept C15744967 @default.
- W2042487309 hasConcept C169760540 @default.
- W2042487309 hasConcept C2775855016 @default.