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- W2042531831 abstract "Hemorrhagic proteinase, HTb, isolated from Crotalus atrox (western diamondback rattlesnake) venom was studied for its specificity. HTb showed fibrinogenase activity, hydrolyzing the A alpha chain of fibrinogen first, followed by the cleavage of the B beta chain. HTb is different from thrombin and did not produce a fibrin clot. The degradation products of fibrinogen were found to be different, indicating that the cleavage sites in the A alpha and B beta chains are different from those of thrombin. N-Benzoyl-Phe-Val-Arg-p-nitroanilide was not hydrolyzed by HTb, although this substrate was hydrolyzed by thrombin and reptilase." @default.
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- W2042531831 date "1985-05-01" @default.
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- W2042531831 title "Specificity of hemorrhagic proteinase from Crotalus atrox (western diamondback rattlesnake) venom" @default.
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- W2042531831 doi "https://doi.org/10.1016/0167-4838(85)90076-7" @default.
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