Matches in SemOpenAlex for { <https://semopenalex.org/work/W2042557809> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2042557809 endingPage "160" @default.
- W2042557809 startingPage "155" @default.
- W2042557809 abstract "A monoclonal antibody (mAb 33.4) is described which inhibits the adhesion and spreading of an adherent cell line (A-cells), established from Morris hepatoma 7777 and isolated hepatocytes on collagen IV but not on laminin, fibronectin, and vitronectin. mAb 33.4 retains its immunological activity after immobilization and covalent cross-linking to Protein G-Sepharose and is therefore a suitable tool for the preparative equimolar purification of two proteins with Mr of 130 and 190 kDa from detergent-solubilized membrane fractions by immunoaffinity chromatography. The 190-kDa protein was identified as rat α1-integrin subunit by N-terminal amino acid sequencing, while the 130-kDa protein was specifically stained by a β1-integrin subunit-specific antiserum. In immunoblot analysis mAb 33.4 recognized the 190-kDa band, suggesting that it is specific for the rat α1-integrin subunit. The epitope recognized by mAb 33.4 is conformation-dependent because the staining in immunoblots was very strong if the SDS-PAGE was performed in the absence of reducing agents. The expression of α1β1-integrin in sinusoidal hepatocyte membrane domains of liver sections is shown by mAb 33.4 and antisera raised against the rat α1- and β1-integrin subunits." @default.
- W2042557809 created "2016-06-24" @default.
- W2042557809 creator A5001753251 @default.
- W2042557809 creator A5013363808 @default.
- W2042557809 creator A5032586373 @default.
- W2042557809 creator A5040405873 @default.
- W2042557809 creator A5079723288 @default.
- W2042557809 date "1994-05-01" @default.
- W2042557809 modified "2023-09-24" @default.
- W2042557809 title "Cell-Collagen Adhesion Is Inhibited by Monoclonal Antibody 33.4 against the Rat α1-Integrin Subunit" @default.
- W2042557809 doi "https://doi.org/10.1006/excr.1994.1130" @default.
- W2042557809 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7513646" @default.
- W2042557809 hasPublicationYear "1994" @default.
- W2042557809 type Work @default.
- W2042557809 sameAs 2042557809 @default.
- W2042557809 citedByCount "27" @default.
- W2042557809 countsByYear W20425578092014 @default.
- W2042557809 crossrefType "journal-article" @default.
- W2042557809 hasAuthorship W2042557809A5001753251 @default.
- W2042557809 hasAuthorship W2042557809A5013363808 @default.
- W2042557809 hasAuthorship W2042557809A5032586373 @default.
- W2042557809 hasAuthorship W2042557809A5040405873 @default.
- W2042557809 hasAuthorship W2042557809A5079723288 @default.
- W2042557809 hasConcept C104292427 @default.
- W2042557809 hasConcept C104317684 @default.
- W2042557809 hasConcept C1491633281 @default.
- W2042557809 hasConcept C153911025 @default.
- W2042557809 hasConcept C159654299 @default.
- W2042557809 hasConcept C164144092 @default.
- W2042557809 hasConcept C179247698 @default.
- W2042557809 hasConcept C181199279 @default.
- W2042557809 hasConcept C189165786 @default.
- W2042557809 hasConcept C195616568 @default.
- W2042557809 hasConcept C195687474 @default.
- W2042557809 hasConcept C203014093 @default.
- W2042557809 hasConcept C2779814568 @default.
- W2042557809 hasConcept C2779881004 @default.
- W2042557809 hasConcept C542903549 @default.
- W2042557809 hasConcept C55493867 @default.
- W2042557809 hasConcept C86492073 @default.
- W2042557809 hasConcept C86803240 @default.
- W2042557809 hasConcept C91523082 @default.
- W2042557809 hasConceptScore W2042557809C104292427 @default.
- W2042557809 hasConceptScore W2042557809C104317684 @default.
- W2042557809 hasConceptScore W2042557809C1491633281 @default.
- W2042557809 hasConceptScore W2042557809C153911025 @default.
- W2042557809 hasConceptScore W2042557809C159654299 @default.
- W2042557809 hasConceptScore W2042557809C164144092 @default.
- W2042557809 hasConceptScore W2042557809C179247698 @default.
- W2042557809 hasConceptScore W2042557809C181199279 @default.
- W2042557809 hasConceptScore W2042557809C189165786 @default.
- W2042557809 hasConceptScore W2042557809C195616568 @default.
- W2042557809 hasConceptScore W2042557809C195687474 @default.
- W2042557809 hasConceptScore W2042557809C203014093 @default.
- W2042557809 hasConceptScore W2042557809C2779814568 @default.
- W2042557809 hasConceptScore W2042557809C2779881004 @default.
- W2042557809 hasConceptScore W2042557809C542903549 @default.
- W2042557809 hasConceptScore W2042557809C55493867 @default.
- W2042557809 hasConceptScore W2042557809C86492073 @default.
- W2042557809 hasConceptScore W2042557809C86803240 @default.
- W2042557809 hasConceptScore W2042557809C91523082 @default.
- W2042557809 hasIssue "1" @default.
- W2042557809 hasLocation W20425578091 @default.
- W2042557809 hasLocation W20425578092 @default.
- W2042557809 hasOpenAccess W2042557809 @default.
- W2042557809 hasPrimaryLocation W20425578091 @default.
- W2042557809 hasRelatedWork W1998568914 @default.
- W2042557809 hasRelatedWork W2004397662 @default.
- W2042557809 hasRelatedWork W2033391402 @default.
- W2042557809 hasRelatedWork W2035660111 @default.
- W2042557809 hasRelatedWork W2041863296 @default.
- W2042557809 hasRelatedWork W2079798045 @default.
- W2042557809 hasRelatedWork W2187687342 @default.
- W2042557809 hasRelatedWork W2335866695 @default.
- W2042557809 hasRelatedWork W2338894968 @default.
- W2042557809 hasRelatedWork W2395439073 @default.
- W2042557809 hasVolume "212" @default.
- W2042557809 isParatext "false" @default.
- W2042557809 isRetracted "false" @default.
- W2042557809 magId "2042557809" @default.
- W2042557809 workType "article" @default.