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• W2042669137 abstract "A new series of oxazolidinones bearing N-linked 5-triazolylmethyl group have been synthesized and their in vitro antibacterial activities (MIC) were evaluated against a spectrum of resistant and susceptible Gram-positive organisms. Some of the analogues in this series displayed activity superior to linezolid and vancomycin. Furthermore, in vivo efficacies and pharmacokinetic properties of the selected compounds were also disclosed herein; the selected compounds showed reasonable bioavailability as well as in vivo efficacy comparable to that of linezolid." @default.
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• W2042669137 date "2008-08-01" @default.
• W2042669137 modified "2023-09-27" @default.
• W2042669137 title "Synthesis and biological evaluation of new N-linked 5-triazolylmethyl oxazolidinones" @default.
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• W2042669137 doi "https://doi.org/10.1016/j.ejmech.2007.09.010" @default.
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