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- W2042732498 abstract "The resurgence of syphilis infection with the migration of many women from the undeveloped countries is a reason for concern considering the possible occurrence of congenital syphilis (CS). A 28year-old VI gravida 6, para 2 was referred to our Unit at 24 weeks of gestation with a suspicion of fetal infection for the presence of hyperechoic bowel. The patient has been screened only for syphilis at 13 weeks of gestation. The test (TPHA-Treponema method CLIA 57.9; V.N < 0.9) resulted positive. After repetition of TPHA with FTA/ABS during 25th weeks and the confirmation of the positivity, the patient began the therapy with benzyl penicillin. The transabdominal ultrasound examination showed a stillborn fetus. We observed hyperechoic bowel, hepatosplenomegaly, ascites, placentomegaly. This constellation of sonographic findings should raise suspicion of syphilis infection of the fetus. Fetal biometry was correspondent. After delivery, fetal-placental examination and autopsy showed clinical findings typical of congenital syphilis. Congenital hearth malformation characterized by aortic and left ventricular hypoplasia was also present. This positive serological pattern in the absence of clinical manifestations can be considered a case of untreated latent syphilis of unknown duration. The fetal ultrasound morphological abnormalities observed in congenital syphilis must be considered also in our country and the resurgence of syphilis infection supports the recommendation of screening and effective treatment of syphilis in the first trimester." @default.
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- W2042732498 date "2009-09-01" @default.
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- W2042732498 title "P15.04: Congenital syphilis" @default.
- W2042732498 doi "https://doi.org/10.1002/uog.7204" @default.
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