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• W2042740655 abstract "The purpose of the study was to determine the effectiveness of a prophylactic total coronary care regime. Treatment commenced at home, continued in hospital with or without cardiographic monitoring, and extended to posthospitalization rehabilitation. Results were assessed according to four week and one year mortality, the effectiveness of treating and preventing early and late complications, and the degree of rehabilitation. Such assessment is the first of its kind reported in the literature. A prospective study of 100 consecutive infarct patients of whom the first 46 were unmonitored and the remaining 54 monitored were found comparable to each other and to the reported series as assessed according to accepted prognostic factors. The series differed in that patients were seen at an earlier stage with more frequent cardiac slowing and with a lower incidence of cardiogenic shock and the monitored patients were older. The hospital mortality rate was 10 per cent and the one year mortality rate a further 9 per cent. The over-all mortality rate is the lowest so far reported. Response to treatment of arrhythmias was 85 per cent, of cardiac failure to furosemide 77 per cent, and a further 12 per cent responded to additional digoxin. Hypotension was reverted in 90 per cent when associated with bradyarrhythmias and cardiogenic shock was reverted in 50 per cent. Angina disappeared in 27 per cent of those with angina prior to infarction. Prevention of complications during hospitalization was effective. Only one patient developed cardiac arrest due to ventricular fibrillation. Of the monitored patients 20 per cent developed arrhythmias and these were rarely serious. Eleven per cent of the total developed cardiac failure and 4 per cent reinfarcted. Post-hospitalization complications within 12 months were cardiac failure in 11 per cent and developing angina in 13 per cent. Half the patients were fully rehabilitated and one quarter had been and remained retired. Eighty per cent returned to work. Under this prophylactic regimen, results did not significantly differ in the monitored and unmonitored series. It is concluded that a prophylactic treatment regimen commencing in the prehospital phase effectively reduces mortality and morbidity of myocardial infarction. The regimen is applicable when monitoring facilities are not available." @default.
• W2042740655 created "2016-06-24" @default.
• W2042740655 creator A5018051217 @default.
• W2042740655 date "1973-06-01" @default.
• W2042740655 modified "2023-09-25" @default.
• W2042740655 title "Prophylactic total coronary care" @default.
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• W2042740655 doi "https://doi.org/10.1016/0002-8703(73)90433-x" @default.
• W2042740655 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4702668" @default.
• W2042740655 hasPublicationYear "1973" @default.
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