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- W2042753434 abstract "The effects of serotonin (5-HT) on a beta-adrenergic response were studied, using the voltage clamp technique, in Xenopus laevis oocytes surrounded by their follicular cells. noradrenaline induced marked hyperpolarization, with a specific increase in the permeability of the membrane toward K+. Application of 10 microM 5-HT had little effect on the resting membrane, but significantly depressed the response to 0.1 microM noradrenaline. The dose-response curve for noradrenaline showed a parallel shift to the right in the presence of 5-HT, suggesting that 5-HT competes with noradrenaline for common binding sites at the beta-adrenoceptor." @default.
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- W2042753434 date "1993-08-01" @default.
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- W2042753434 title "Blocking effect of serotonin on β-adrenoceptor activity in follicle-enclosed Xenopus oocytes" @default.
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- W2042753434 doi "https://doi.org/10.1016/0014-2999(93)90901-s" @default.
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