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• W2042870974 abstract "In this paper we present a method to fabricate an aperture in a silicon wafer that can be used to suspend a freestanding lipid bilayer membrane. The design offers the feature of scalability of the aperture size into the submicron range. Lipid bilayer membranes formed across the aperture in the oxidized silicon substrate show a gigaohm sealing resistance. The stability of these membranes allowed the insertion of a nanometer-sized ion channel protein (OmpF porin) and the measurement of voltage dependent gating that can be expected from a working porin ion channel." @default.
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• W2042870974 date "2003-09-01" @default.
• W2042870974 modified "2023-09-27" @default.
• W2042870974 title "Silicon-based ion channel sensor" @default.
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• W2042870974 doi "https://doi.org/10.1016/j.spmi.2004.03.041" @default.
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