Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043067191> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2043067191 endingPage "1585" @default.
- W2043067191 startingPage "1579" @default.
- W2043067191 abstract "In our clinical experience combining wide excision and intraoperative radiotherapy (IORT), five patients have developed clinical signs of lumbosacral or sciatic neuropathy within 9 months of receiving IORT to a dose of 20-25 Gy. Three patients showed recovery of nerve function over several months while two patients have shown no recovery and have near complete loss of extremity function. In an attempt to investigate this clinical observation further, the lumbosacral plexus and sciatic nerve of American foxhounds were surgically exposed and received a single dose of IORT ranging from 20-75 Gy. An approximate linear relationship between radiation dose and time to onset of hind limb paresis is found with 19 of 21 irradiated dogs showing clinical signs of nerve injury within an interval of 1-19 months. No recovery of nerve function is seen in these dogs. Histological study of the irradiated nerves demonstrates a loss of nerve fibers, particularly those of the large myelinated type without evidence of vascular occlusion or thrombosis. These studies suggest that peripheral nerve may be a dose-limiting normal tissue in clinical studies of IORT." @default.
- W2043067191 created "2016-06-24" @default.
- W2043067191 creator A5022359101 @default.
- W2043067191 creator A5024098703 @default.
- W2043067191 creator A5034862708 @default.
- W2043067191 creator A5035162312 @default.
- W2043067191 creator A5038738545 @default.
- W2043067191 creator A5060103832 @default.
- W2043067191 creator A5062983137 @default.
- W2043067191 creator A5070481239 @default.
- W2043067191 creator A5072133376 @default.
- W2043067191 creator A5076561146 @default.
- W2043067191 creator A5088042047 @default.
- W2043067191 creator A5089798708 @default.
- W2043067191 date "1985-09-01" @default.
- W2043067191 modified "2023-10-13" @default.
- W2043067191 title "Tolerance of peripheral nerve to intraoperative radiotherapy (IORT): Clinical and experimental studies" @default.
- W2043067191 cites W138695865 @default.
- W2043067191 cites W1965322457 @default.
- W2043067191 cites W1969749496 @default.
- W2043067191 cites W2033573484 @default.
- W2043067191 cites W2053747607 @default.
- W2043067191 cites W2054922815 @default.
- W2043067191 cites W2065186455 @default.
- W2043067191 cites W2074375792 @default.
- W2043067191 cites W2131039000 @default.
- W2043067191 cites W2167167226 @default.
- W2043067191 cites W4239817271 @default.
- W2043067191 cites W4298470319 @default.
- W2043067191 doi "https://doi.org/10.1016/0360-3016(85)90209-3" @default.
- W2043067191 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4030429" @default.
- W2043067191 hasPublicationYear "1985" @default.
- W2043067191 type Work @default.
- W2043067191 sameAs 2043067191 @default.
- W2043067191 citedByCount "119" @default.
- W2043067191 countsByYear W20430671912012 @default.
- W2043067191 countsByYear W20430671912013 @default.
- W2043067191 countsByYear W20430671912014 @default.
- W2043067191 countsByYear W20430671912015 @default.
- W2043067191 countsByYear W20430671912016 @default.
- W2043067191 countsByYear W20430671912017 @default.
- W2043067191 countsByYear W20430671912018 @default.
- W2043067191 countsByYear W20430671912019 @default.
- W2043067191 countsByYear W20430671912020 @default.
- W2043067191 countsByYear W20430671912022 @default.
- W2043067191 countsByYear W20430671912023 @default.
- W2043067191 crossrefType "journal-article" @default.
- W2043067191 hasAuthorship W2043067191A5022359101 @default.
- W2043067191 hasAuthorship W2043067191A5024098703 @default.
- W2043067191 hasAuthorship W2043067191A5034862708 @default.
- W2043067191 hasAuthorship W2043067191A5035162312 @default.
- W2043067191 hasAuthorship W2043067191A5038738545 @default.
- W2043067191 hasAuthorship W2043067191A5060103832 @default.
- W2043067191 hasAuthorship W2043067191A5062983137 @default.
- W2043067191 hasAuthorship W2043067191A5070481239 @default.
- W2043067191 hasAuthorship W2043067191A5072133376 @default.
- W2043067191 hasAuthorship W2043067191A5076561146 @default.
- W2043067191 hasAuthorship W2043067191A5088042047 @default.
- W2043067191 hasAuthorship W2043067191A5089798708 @default.
- W2043067191 hasConcept C141071460 @default.
- W2043067191 hasConcept C2776613520 @default.
- W2043067191 hasConcept C2779494622 @default.
- W2043067191 hasConcept C2781149210 @default.
- W2043067191 hasConcept C42219234 @default.
- W2043067191 hasConcept C509974204 @default.
- W2043067191 hasConcept C7146039 @default.
- W2043067191 hasConcept C71924100 @default.
- W2043067191 hasConceptScore W2043067191C141071460 @default.
- W2043067191 hasConceptScore W2043067191C2776613520 @default.
- W2043067191 hasConceptScore W2043067191C2779494622 @default.
- W2043067191 hasConceptScore W2043067191C2781149210 @default.
- W2043067191 hasConceptScore W2043067191C42219234 @default.
- W2043067191 hasConceptScore W2043067191C509974204 @default.
- W2043067191 hasConceptScore W2043067191C7146039 @default.
- W2043067191 hasConceptScore W2043067191C71924100 @default.
- W2043067191 hasIssue "9" @default.
- W2043067191 hasLocation W20430671911 @default.
- W2043067191 hasLocation W20430671912 @default.
- W2043067191 hasOpenAccess W2043067191 @default.
- W2043067191 hasPrimaryLocation W20430671911 @default.
- W2043067191 hasRelatedWork W1990002036 @default.
- W2043067191 hasRelatedWork W2000408044 @default.
- W2043067191 hasRelatedWork W2060044186 @default.
- W2043067191 hasRelatedWork W2068180808 @default.
- W2043067191 hasRelatedWork W2108246414 @default.
- W2043067191 hasRelatedWork W2166385392 @default.
- W2043067191 hasRelatedWork W2389642814 @default.
- W2043067191 hasRelatedWork W2562676173 @default.
- W2043067191 hasRelatedWork W2930216454 @default.
- W2043067191 hasRelatedWork W3023404500 @default.
- W2043067191 hasVolume "11" @default.
- W2043067191 isParatext "false" @default.
- W2043067191 isRetracted "false" @default.
- W2043067191 magId "2043067191" @default.
- W2043067191 workType "article" @default.