FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043074041> ?p ?o ?g. }

• W2043074041 abstract "Volatile anesthetics have been shown to dilate cerebral vessels. Recent evidence suggests that mild hypothermia can alter vascular reactivity of the cerebral vessels. However, the effect of mild hypothermia on volatile anesthetic-induced vasodilation of cerebral vessels is unknown. In the present study, we investigated the effect of mild hypothermia on pial arteriolar vasodilation induced by isoflurane and sevoflurane in cats.Prospective, randomized, experimental study with repeated measures.Investigational animal laboratory.Forty cats were used for the study of systemic administration of volatile anesthetics, and 22 cats were used for the study of topical administration of volatile anesthetics.This study was approved by the Animal Experiment Committee of Nara Medical University. Animals were anesthetized with pentobarbital to maintain suppressive electroencephalographic patterns, which were introduced to measure direct effects of anesthetic agents after removing metabolic effects. The cranial window technique, combined with microscopic video recording, was used for the measurement of small (50-100 microm) and large (100-200 microm) pial arteriolar diameter in an experiment. Animals were randomly assigned to either a normothermic (37 degrees C) or a hypothermic group (33 degrees C). Desired temperatures were maintained by using a water blanket. In the first phase of the study, the effect of hypothermia on pial arteriolar vasodilation induced by systemic administration of isoflurane or sevoflurane was assessed. Each cat received isoflurane or sevoflurane at 0.5, 1.0, 1.5, and 2.0 minimum alveolar anesthetic concentrations, and the diameter of pial arterioles was measured. In the second group of animals, the direct effect of isoflurane and sevoflurane on pial vessels was evaluated. The artificial cerebrospinal fluid bubbled with isoflurane or sevoflurane (minimum alveolar anesthetic concentrations of 1 or 3) was topically administered in the cranial window.Systemic and topical administration of isoflurane and sevoflurane produced significant dilation of both small and large pial arterioles in a dose-dependent manner during normothermia. In the hypothermic group, vasodilation of small pial arterioles by systemic administration of isoflurane and sevoflurane at a high concentration was significantly larger than in the normothermic group (p <.05). Vasodilation of both small and large pial arterioles by topical administration of isoflurane and sevoflurane was significantly greater in the hypothermic group than in the normothermic group (p <.05).These results suggest that pial arteriolar vasodilation induced by isoflurane and sevoflurane can be enhanced by mild hypothermia in cats anesthetized with pentobarbital." @default.
• W2043074041 created "2016-06-24" @default.
• W2043074041 creator A5013327405 @default.
• W2043074041 creator A5015844942 @default.
• W2043074041 creator A5019464359 @default.
• W2043074041 creator A5034199030 @default.
• W2043074041 creator A5035541324 @default.
• W2043074041 creator A5064819878 @default.
• W2043074041 creator A5077835734 @default.
• W2043074041 creator A5078754292 @default.
• W2043074041 date "2002-08-01" @default.
• W2043074041 modified "2023-09-24" @default.
• W2043074041 title "Mild hypothermia can enhance pial arteriolar vasodilation induced by isoflurane and sevoflurane in cats" @default.
• W2043074041 cites W1894516642 @default.
• W2043074041 cites W1966351881 @default.
• W2043074041 cites W1971118793 @default.
• W2043074041 cites W1997834318 @default.
• W2043074041 cites W2002921620 @default.
• W2043074041 cites W2004352086 @default.
• W2043074041 cites W2011944656 @default.
• W2043074041 cites W2020385862 @default.
• W2043074041 cites W2020473277 @default.
• W2043074041 cites W2022662866 @default.
• W2043074041 cites W2038478540 @default.
• W2043074041 cites W2042985858 @default.
• W2043074041 cites W2043836154 @default.
• W2043074041 cites W2051422097 @default.
• W2043074041 cites W2058719241 @default.
• W2043074041 cites W2068187883 @default.
• W2043074041 cites W2080656191 @default.
• W2043074041 cites W2080772690 @default.
• W2043074041 cites W2087776022 @default.
• W2043074041 cites W2089133038 @default.
• W2043074041 cites W2091036436 @default.
• W2043074041 cites W2093683788 @default.
• W2043074041 cites W2096182033 @default.
• W2043074041 cites W2101519656 @default.
• W2043074041 cites W2117750331 @default.
• W2043074041 cites W2119945315 @default.
• W2043074041 cites W2123841491 @default.
• W2043074041 cites W2126204041 @default.
• W2043074041 cites W2128811231 @default.
• W2043074041 cites W2131595097 @default.
• W2043074041 cites W2134763213 @default.
• W2043074041 cites W2163329399 @default.
• W2043074041 cites W4253795603 @default.
• W2043074041 doi "https://doi.org/10.1097/00003246-200208000-00032" @default.
• W2043074041 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12163807" @default.
• W2043074041 hasPublicationYear "2002" @default.
• W2043074041 type Work @default.
• W2043074041 sameAs 2043074041 @default.
• W2043074041 citedByCount "7" @default.
• W2043074041 countsByYear W20430740412012 @default.
• W2043074041 countsByYear W20430740412014 @default.
• W2043074041 countsByYear W20430740412016 @default.
• W2043074041 countsByYear W20430740412021 @default.
• W2043074041 crossrefType "journal-article" @default.
• W2043074041 hasAuthorship W2043074041A5013327405 @default.
• W2043074041 hasAuthorship W2043074041A5015844942 @default.
• W2043074041 hasAuthorship W2043074041A5019464359 @default.
• W2043074041 hasAuthorship W2043074041A5034199030 @default.
• W2043074041 hasAuthorship W2043074041A5035541324 @default.
• W2043074041 hasAuthorship W2043074041A5064819878 @default.
• W2043074041 hasAuthorship W2043074041A5077835734 @default.
• W2043074041 hasAuthorship W2043074041A5078754292 @default.
• W2043074041 hasConcept C120770815 @default.
• W2043074041 hasConcept C126322002 @default.
• W2043074041 hasConcept C2776359302 @default.
• W2043074041 hasConcept C2777390192 @default.
• W2043074041 hasConcept C2778162923 @default.
• W2043074041 hasConcept C2779904517 @default.
• W2043074041 hasConcept C2781453256 @default.
• W2043074041 hasConcept C42219234 @default.
• W2043074041 hasConcept C71924100 @default.
• W2043074041 hasConceptScore W2043074041C120770815 @default.
• W2043074041 hasConceptScore W2043074041C126322002 @default.
• W2043074041 hasConceptScore W2043074041C2776359302 @default.
• W2043074041 hasConceptScore W2043074041C2777390192 @default.
• W2043074041 hasConceptScore W2043074041C2778162923 @default.
• W2043074041 hasConceptScore W2043074041C2779904517 @default.
• W2043074041 hasConceptScore W2043074041C2781453256 @default.
• W2043074041 hasConceptScore W2043074041C42219234 @default.
• W2043074041 hasConceptScore W2043074041C71924100 @default.
• W2043074041 hasLocation W20430740411 @default.
• W2043074041 hasLocation W20430740412 @default.
• W2043074041 hasOpenAccess W2043074041 @default.
• W2043074041 hasPrimaryLocation W20430740411 @default.
• W2043074041 hasRelatedWork W1972258102 @default.
• W2043074041 hasRelatedWork W1974892472 @default.
• W2043074041 hasRelatedWork W1978505987 @default.
• W2043074041 hasRelatedWork W1980908936 @default.
• W2043074041 hasRelatedWork W1982088891 @default.
• W2043074041 hasRelatedWork W1988311680 @default.
• W2043074041 hasRelatedWork W1991389031 @default.
• W2043074041 hasRelatedWork W2007655592 @default.
• W2043074041 hasRelatedWork W2016911954 @default.
• W2043074041 hasRelatedWork W2026873786 @default.
• W2043074041 hasRelatedWork W2027572131 @default.
• W2043074041 hasRelatedWork W2037432097 @default.
• W2043074041 hasRelatedWork W2058904384 @default.

• next