Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043084865> ?p ?o ?g. }
- W2043084865 endingPage "2258" @default.
- W2043084865 startingPage "2248" @default.
- W2043084865 abstract "Acute heart failure syndromes (AHFS) remain a major cause of morbidity and mortality, in part because the development of new therapies for these disorders has been marked by frequent failure and little success. The heterogeneity of current approaches to AHFS drug development, particularly with regard to end points, remains a major potential barrier to progress in the field. End points involving hemodynamic status, biomarkers, symptoms, hospital stay, end organ function, and mortality have all been employed either alone or in combination in recent randomized clinical trials in AHFS. In this review, we will discuss the various end point domains from both a clinical and a statistical perspective, summarize the wide variety of end points used in completed and ongoing AHFS studies, and suggest steps for greater standardization of end points across AHFS trials." @default.
- W2043084865 created "2016-06-24" @default.
- W2043084865 creator A5012849300 @default.
- W2043084865 creator A5015595507 @default.
- W2043084865 creator A5022076272 @default.
- W2043084865 creator A5087791202 @default.
- W2043084865 date "2009-06-01" @default.
- W2043084865 modified "2023-09-26" @default.
- W2043084865 title "End Points for Clinical Trials in Acute Heart Failure Syndromes" @default.
- W2043084865 cites W1418063743 @default.
- W2043084865 cites W172609984 @default.
- W2043084865 cites W1748068649 @default.
- W2043084865 cites W1875039943 @default.
- W2043084865 cites W1975971363 @default.
- W2043084865 cites W1988232724 @default.
- W2043084865 cites W1988816170 @default.
- W2043084865 cites W1993823264 @default.
- W2043084865 cites W2013009184 @default.
- W2043084865 cites W2030881336 @default.
- W2043084865 cites W2034907954 @default.
- W2043084865 cites W2038630181 @default.
- W2043084865 cites W2038813835 @default.
- W2043084865 cites W2042805913 @default.
- W2043084865 cites W2050348223 @default.
- W2043084865 cites W2057956109 @default.
- W2043084865 cites W2058542276 @default.
- W2043084865 cites W2080164795 @default.
- W2043084865 cites W2087948512 @default.
- W2043084865 cites W2090544953 @default.
- W2043084865 cites W2091057702 @default.
- W2043084865 cites W2100334454 @default.
- W2043084865 cites W2103711003 @default.
- W2043084865 cites W2112636786 @default.
- W2043084865 cites W2119061468 @default.
- W2043084865 cites W2119875370 @default.
- W2043084865 cites W2120289695 @default.
- W2043084865 cites W2122074886 @default.
- W2043084865 cites W2126271215 @default.
- W2043084865 cites W2126426045 @default.
- W2043084865 cites W2127125241 @default.
- W2043084865 cites W2141703599 @default.
- W2043084865 cites W2147588039 @default.
- W2043084865 cites W2155949904 @default.
- W2043084865 cites W2157098785 @default.
- W2043084865 cites W2164846898 @default.
- W2043084865 cites W2164902492 @default.
- W2043084865 cites W2166780351 @default.
- W2043084865 cites W2168017932 @default.
- W2043084865 cites W2169475898 @default.
- W2043084865 cites W2169560588 @default.
- W2043084865 cites W2186657631 @default.
- W2043084865 cites W2212004723 @default.
- W2043084865 cites W2299836127 @default.
- W2043084865 cites W2615043561 @default.
- W2043084865 cites W2912227678 @default.
- W2043084865 cites W4235318691 @default.
- W2043084865 cites W4249847277 @default.
- W2043084865 doi "https://doi.org/10.1016/j.jacc.2008.12.079" @default.
- W2043084865 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3961583" @default.
- W2043084865 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19520247" @default.
- W2043084865 hasPublicationYear "2009" @default.
- W2043084865 type Work @default.
- W2043084865 sameAs 2043084865 @default.
- W2043084865 citedByCount "95" @default.
- W2043084865 countsByYear W20430848652012 @default.
- W2043084865 countsByYear W20430848652013 @default.
- W2043084865 countsByYear W20430848652014 @default.
- W2043084865 countsByYear W20430848652015 @default.
- W2043084865 countsByYear W20430848652016 @default.
- W2043084865 countsByYear W20430848652017 @default.
- W2043084865 countsByYear W20430848652018 @default.
- W2043084865 countsByYear W20430848652019 @default.
- W2043084865 countsByYear W20430848652020 @default.
- W2043084865 countsByYear W20430848652021 @default.
- W2043084865 countsByYear W20430848652022 @default.
- W2043084865 crossrefType "journal-article" @default.
- W2043084865 hasAuthorship W2043084865A5012849300 @default.
- W2043084865 hasAuthorship W2043084865A5015595507 @default.
- W2043084865 hasAuthorship W2043084865A5022076272 @default.
- W2043084865 hasAuthorship W2043084865A5087791202 @default.
- W2043084865 hasBestOaLocation W20430848652 @default.
- W2043084865 hasConcept C126322002 @default.
- W2043084865 hasConcept C164705383 @default.
- W2043084865 hasConcept C177713679 @default.
- W2043084865 hasConcept C2524010 @default.
- W2043084865 hasConcept C2778198053 @default.
- W2043084865 hasConcept C2987804222 @default.
- W2043084865 hasConcept C33923547 @default.
- W2043084865 hasConcept C535046627 @default.
- W2043084865 hasConcept C71924100 @default.
- W2043084865 hasConceptScore W2043084865C126322002 @default.
- W2043084865 hasConceptScore W2043084865C164705383 @default.
- W2043084865 hasConceptScore W2043084865C177713679 @default.
- W2043084865 hasConceptScore W2043084865C2524010 @default.
- W2043084865 hasConceptScore W2043084865C2778198053 @default.
- W2043084865 hasConceptScore W2043084865C2987804222 @default.
- W2043084865 hasConceptScore W2043084865C33923547 @default.
- W2043084865 hasConceptScore W2043084865C535046627 @default.