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- W2043138086 abstract "Forty-nine biopsy specimens of nasopharyngeal carcinoma and 20 biopsy specimens of nasopharyngeal mucosa obtained from non-cancer patients were studied for the presence of T-zone histiocytes (Langerhans' cells and their precursors) and macrophages by immunohistochemical methods with the use of antibodies against S-100 protein and lysozyme (lys), respectively. Patients with dense infiltration of T-zone histiocytes in the primary sites survived longer than those without such infiltration (mean survival times, 8, 39, and 72 months in the patients with the density of -, +, and ++, respectively; P less than 0.005). In contrast, there was no relationship between patient prognosis and density of lys+ macrophages in the tumor tissue (P = 0.33). The distribution of T-zone histiocytes in the tumor tissue was different from that of macrophages. T-zone histiocytes may play an important role in the immune reaction against cancer, probably acting through mechanism different from that of macrophages." @default.
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- W2043138086 date "1986-01-01" @default.
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- W2043138086 title "Histiocytes in nasopharyngeal carcinoma in relation to prognosis" @default.
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- W2043138086 doi "https://doi.org/10.1002/1097-0142(19860101)57:1<100::aid-cncr2820570121>3.0.co;2-x" @default.
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