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- W2043138850 abstract "We developed a new protocol for the cyanoethylation of the hydroxyl function of nucleosides. A new system of Cs2CO3-tBuOH proved to be the best for the cyanoethylation. An oligonucleotide incorporating 2′-O-cyanoethylated uridine has high affinity (ΔTm = 0.6 °C/modification) for the complementary DNA or RNA strand than the corresponding 2′-O-methyl-RNA." @default.
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- W2043138850 date "2004-11-01" @default.
- W2043138850 modified "2023-09-23" @default.
- W2043138850 title "Synthesis and properties of 2'-O-cyanoethylated RNA derivatives" @default.
- W2043138850 doi "https://doi.org/10.1093/nass/48.1.13" @default.
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