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• W2043182808 abstract "LEUKEMIA IN ATLANTA, GEORGIA G. E. Alan D ever* This paper is an exploratory intra-urban medical geographic study. Its purpose is to illustrate the spatial pattern of acute/sub-acute leu­ kemia incidence in the city of Atlanta. (1) Further, the paper will analyze various social, economic, and demographic variables that may be related to the spatial pattern of leukemia. (2) The variables selected for testing are those that reflect a hypothesis of a viral etiology. (3) The viral etiology hypothesis reflects the theory that leukemia is caused by an infectious agent. If this is so, one would expect higher rates of leukemia in areas that are conducive to the transmission of an infectious disease. Thus, areas of high and low leukemia incidence are designated as high and low risk areas. The correlations obtained for all areas (census tracts) are statistically significant. Subsequent analysis of the low risk areas showed significantly higher correlations, whereas the correlations were poor for the high risk areas. Therefore, meaningful associations for low risk areas can be determined but the factors relating to leukemia high risk areas are not so apparent. SPATIAL DISTRIBUTION OF LEUKEMIA IN ATLANTA. The spatial pattern of acute/sub-ac^te leukemia in Atlanta reveals a clear pattern of high rate and low rate areas (Figure 1). The high rates of leukemia, which range from 9.0 to 16.9 per 100,000, appear to cluster near the central city with one or two of these areas randomly distributed. The low rates range from 0.0 to 3.0 per 100,000 and show a contiguous rather than a clustered distribution. These areas of high and low leukemia rates may be considered areas of high and low risk. (4) These areas are investi­ gated to determine the relationship of leukemia risk to selected social, economic, and demographic variables. The map of leukemia incidence is based on all acute and sub-acute cases for all ages for the years 1960 through 1969. The 1965 estimated population of Atlanta was used to calculate the rates. (5) The frequency polygon of the incidence rates (Figure 1) shows a positive skewed dis­ tribution, indicating that there are many low rates with relatively few high rates. It is apparent from the spatial pattern and the frequency polygon that the distribution of leukemia incidence reflects both geo­ graphical and statistical peculiarities. This study accounts for these peculiarities through the use of step-wise regression and correlation analysis. *Dr. Dever is assistant professor of geography at Georgia State University. The paper was accepted for publication in June 1972. 92 Sou th eastern G eographer LEUKEMIA INCIDENCE 1960 - 1969 00 30 90 169 RATE PER 100.000 Figure 1 METHOD OF ANALYSIS. Three different approaches are employed to identify the relationship of selected variables to the incidence rates of leukemia: (1) analysis of all census tracts in the city of Atlanta; (2) analysis of the high risk census tracts; and (3) analysis of the low risk Vol. XII, No. 2 93 census tracts. The method of analysis used is step-wise regression and correlation. The variables that have been selected for testing for associ­ ations with leukemia incidence are shown in Table 1. The table also indicates the hypothesized relationships of the selected variables to leukemia which reflect the theory of a viral etiology, and in a few instances the established relationships are shown. TABLE 1 HYPOTHESIZED RELATIONSHIP OF SELECTED VARIABLES TO LEUKEMIA: ATLANTA, GEORGIA Variables Exact Definition of the Variable Hypothesized relationship with Y X101 Percent of Non-White Inverse X102 Infant Mortality Inverse X103 Percent of Housing Without Plumbing Direct X104 Median Value of the House Inverse X105 Median Rent Inverse Xioe Population Density Direct X107 Percent of Households with 1.01 or Direct more persons per room Xios Median Income Inverse X109 Percent Households with Female as Head Inverse X110 Percent Dependents to Total Population Direct Source: Calculated by author. RESULTS. All Census Tracts. Table 2 shows the results obtained from the step-wise regression and correlation analysis for all census tracts in the city of Atlanta. The results are rather poor as indicated by the cor­ relation coefficient of .2645 which is obtained at..." @default.
• W2043182808 created "2016-06-24" @default.
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• W2043182808 date "1972-01-01" @default.
• W2043182808 modified "2023-10-17" @default.
• W2043182808 title "Leukemia in Atlanta, Georgia" @default.
• W2043182808 cites W2019755446 @default.
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• W2043182808 doi "https://doi.org/10.1353/sgo.1972.0010" @default.
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