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• W2043234212 abstract "In Brief BACKGROUND Increased intracranial pressure (ICP) can cause brain ischemia and compromised brain oxygen (PbtO2 ≤ 20 mm Hg) after severe traumatic brain injury (TBI). OBJECTIVE We examined whether decompressive craniectomy (DC) to treat elevated ICP reduces the cumulative ischemic burden (CIB) of the brain and therapeutic intensity level (TIL). METHODS Ten severe TBI patients (mean age, 31.4 ± 14.2 years) who had continuous PbtO2 monitoring before and after delayed DC were retrospectively identified. Patients were managed according to the guidelines for the management of severe TBI. The CIB was measured as the total time spent between a PbtO2 of 15 to 20, 10 to 15, and 0 to 10 mm Hg. The TIL was calculated every 12 hours. Mixed-effects models were used to estimate changes associated with DC. RESULTS DC was performed on average 2.8 days after admission. DC was found to immediately reduce ICP (mean [SEM] decrease was 7.86 mm Hg [2.4 mm Hg]; P = .005). TIL, which was positively correlated with ICP (r = 0.46, P ≤ .001), was reduced within 12 hours after surgery and continued to improve within the postsurgical monitoring period (P ≤ .001). The duration and severity of CIB were significantly reduced as an effect of DC in this group. The overall mortality rate in the group of 10 patients was lower than predicted at the time of admission (P = .015). CONCLUSION These results suggest that a DC for increased ICP can reduce the CIB of the brain after severe TBI. We suggest that DC be considered early in a patient's clinical course, particularly when the TIL and ICP are increased. BACKGROUND: Increased intracranial pressure (ICP) can cause brain ischemia and compromised brain oxygen (PbtO2 ≤ 20 mm Hg) after severe traumatic brain injury (TBI). OBJECTIVE: We examined whether decompressive craniectomy (DC) to treat elevated ICP reduces the cumulative ischemic burden (CIB) of the brain and therapeutic intensity level (TIL). METHODS: Ten severe TBI patients (mean age, 31.4 ± 14.2 years) who had continuous PbtO2 monitoring before and after delayed DC were retrospectively identified. Patients were managed according to the guidelines for the management of severe TBI. The CIB was measured as the total time spent between a PbtO2 of 15 to 20, 10 to 15, and 0 to 10 mm Hg. The TIL was calculated every 12 hours. Mixed-effects models were used to estimate changes associated with DC. RESULTS: DC was performed on average 2.8 days after admission. DC was found to immediately reduce ICP (mean [SEM] decrease was 7.86 mm Hg [2.4 mm Hg]; P = .005). TIL, which was positively correlated with ICP (r = 0.46, P ≤ .001), was reduced within 12 hours after surgery and continued to improve within the postsurgical monitoring period (P ≤ .001). The duration and severity of CIB were significantly reduced as an effect of DC in this group. The overall mortality rate in the group of 10 patients was lower than predicted at the time of admission (P = .015). CONCLUSION: These results suggest that a DC for increased ICP can reduce the CIB of the brain after severe TBI. We suggest that DC be considered early in a patient's clinical course, particularly when the TIL and ICP are increased." @default.
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• W2043234212 date "2010-06-01" @default.
• W2043234212 modified "2023-10-15" @default.
• W2043234212 title "Decompressive Craniectomy for Elevated Intracranial Pressure and Its Effect on the Cumulative Ischemic Burden and Therapeutic Intensity Levels After Severe Traumatic Brain Injury" @default.
• W2043234212 cites W1449393265 @default.
• W2043234212 cites W1491555408 @default.
• W2043234212 cites W1502176921 @default.
• W2043234212 cites W1603121691 @default.
• W2043234212 cites W1677366313 @default.
• W2043234212 cites W1948023428 @default.
• W2043234212 cites W1965821059 @default.
• W2043234212 cites W1966212698 @default.
• W2043234212 cites W1967605991 @default.
• W2043234212 cites W1979913469 @default.
• W2043234212 cites W1983167284 @default.
• W2043234212 cites W1987580762 @default.
• W2043234212 cites W1987825285 @default.
• W2043234212 cites W1992775079 @default.
• W2043234212 cites W1996760171 @default.
• W2043234212 cites W2002708303 @default.
• W2043234212 cites W2007775657 @default.
• W2043234212 cites W2021524486 @default.
• W2043234212 cites W2024321434 @default.
• W2043234212 cites W2040664092 @default.
• W2043234212 cites W2042863053 @default.
• W2043234212 cites W2047264212 @default.
• W2043234212 cites W2049198982 @default.
• W2043234212 cites W2050558202 @default.
• W2043234212 cites W2055111700 @default.
• W2043234212 cites W2058267482 @default.
• W2043234212 cites W2059000843 @default.
• W2043234212 cites W2069437600 @default.
• W2043234212 cites W2072019643 @default.
• W2043234212 cites W2076347418 @default.
• W2043234212 cites W2076811754 @default.
• W2043234212 cites W2077067643 @default.
• W2043234212 cites W2080760655 @default.
• W2043234212 cites W2087398096 @default.
• W2043234212 cites W2093569692 @default.
• W2043234212 cites W2093631216 @default.
• W2043234212 cites W2097552051 @default.
• W2043234212 cites W2099457690 @default.
• W2043234212 cites W2104897154 @default.
• W2043234212 cites W2109095295 @default.
• W2043234212 cites W2115499284 @default.
• W2043234212 cites W2121275412 @default.
• W2043234212 cites W2124888829 @default.
• W2043234212 cites W2127038193 @default.
• W2043234212 cites W2128712943 @default.
• W2043234212 cites W2129793793 @default.
• W2043234212 cites W2130998199 @default.
• W2043234212 cites W2150833402 @default.
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• W2043234212 cites W2154634289 @default.
• W2043234212 cites W2157756406 @default.
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• W2043234212 cites W4293242440 @default.
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• W2043234212 doi "https://doi.org/10.1227/01.neu.0000369607.71913.3e" @default.
• W2043234212 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20386136" @default.
• W2043234212 hasPublicationYear "2010" @default.
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