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• W2043280114 abstract "Precise knowledge of mutation rate at Y-STRs loci is essential for a correct evaluation of typing results in forensic casework and specially kinship genetic studies. In this study, we have examined 252 confirmed and unrelated father/son sample pairs from Moroccan population using the 17 Y-STR markers DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385a, DYS385b, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, and Y-GATA-H4 of the AmpFlSTR Yfiler™ kit used in routine casework. We observed a total of 15 single repeat mutations between fathers and sons as mutational events. Nine mutations resulted in the gain of a repeat in the son and six resulted in a loss of a repeat. The average mutation rate in the studied sample is 3.5 × 10−3 (95% CI 2–5.8 × 10−3). Furthermore, Y-STRs mutation occurrence seems to be 4 times more frequent than autosomal STRs mutation in this sample." @default.
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• W2043280114 date "2013-09-01" @default.
• W2043280114 modified "2023-10-16" @default.
• W2043280114 title "Mutation rate at 17 Y-STR loci in “Father/Son” pairs from moroccan population" @default.
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• W2043280114 doi "https://doi.org/10.1016/j.legalmed.2013.03.003" @default.
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